SUBJECT INDEX 



927 



of temperature on, 752 



on ATPase, 810-812 



on carboxypeptidase, 813-814 



on a-chymotrypsin, 809-811 



on enolase, 814-815 



on enzyme inhibition, 799-815 



on formation of EI complex, 804-807 



on ion-ion interactions, 248-249 



on papain, 812-813 



on rate of inhibition, 807-809 

 examples of effects on enzymes, 809- 

 815 



for different types of interactions. 248- 

 249 



interpretation in solvent mixtures, 801- 

 802 



methods for changing, 800 

 possible mechanisms involved, 802-804 

 variation with distance, 246-248 



with temperature, 245 

 Diethyl-p-nitrophenyl phosphate, inhi- 

 bition of cholinesterase, 627-628 

 Differential inhibition, in whole animals, 



481-485 

 Diffusion, 



effect on intracellular kinetics, 475-477 

 into cells of different shapes, 475-477 

 limiting enzyme reactions, 34-35 

 of inhibitor from cells, 643 

 of substrates into compartments, 34-35 

 Diffusion-limited inhibition, rate expres- 

 sions for, 575-576 

 Diffusion-limited monolinear chains, 335- 



337 

 Diffusion-limited reactions, transit time 



of, 373-379 

 Diisopropylfluorophosphate, 

 concentration in tissues, 395 

 inhibition of cholinesterase, 493-494 



effect of temperature on, 759-760 



in different tissues, 405 



in vivo, 645-646 



reactivation with aldoximes, 632 

 inhibition of a-chymotrj^isin. 187 



effect of pH on, 707 

 use in determining amino acids at active 

 center, 195 



Dilution, 



of enzyme-inhibitor systems, 76-77 

 on rate of inhibition reversal, 609-611 



Dimercaprol (BAL), 



reversal of heavy metal poisoning, 646 

 of inhibitions by mercurials, 622 



Dimercaprol glucoside, reversal of arsen- 

 ical poisoning, 646 



Dimethylcarbamylcholine, inhibition of 

 cholinesterase, 634-636 



Dimethyl-p-nitrophenyl phosphate, in- 

 hibition of cholinesterase, 627-628 



3,5-Dinitro-o-cresol, inhibition of respi- 

 ration, 



effect of pH on. 731 



2,4-Dinitrophenol (DXP), 



effect on adenine nucleotides and phos- 

 phates in yeast, time relations of, 389 

 on cardiac function. 473 

 on glucose concentration in lymph 

 cells, 504 

 inhibition of ATPase, temperature 

 characteristics of, 797 



of gastric secretion, effects of other 

 inhibitors on, 504-505 

 pH of solutions of. 707 

 secondary effects of, 440-441 

 stimulation of respiration, 10 



effect of temperature on, 784-785 

 uncoupling in regenerative systems, 367 

 uptake by yeast cells, 478, 480 



Dioxane, use in lowering dielectric con- 

 stant, 800-801 



Diphosphoglyceromutase, substrate in- 

 hibition, 112 



Diphosphopyridine nucleotide (DPX), 

 complexes with steroids, 298-299 



Dipolar molecules, interaction energy 

 contributions, in, 244 



Dipole angles, 222 



Dipole-dipole interactions, 211-214 

 contributions of various forces, 243 

 dependence on orientation, 211-213 

 effect of dielectric constant on, 248- 

 249 



