932 



SUBJECT INDEX 



Hydration, 250-259 



differences between cations and anions, 



255 



effect of temperature on, 752 



effect on hapten-antibody binding, 284 



on inhibition of cholinesterase, 288 

 energy, 250-255 



definition of, 250 



example of calculation of, 252-255 



of common ions, 251 

 enthalpy, 251 

 entropy, 251 

 free energy, 251 



importance in enzyme interactions, 259 

 in mixed solvents, 802 

 numbers, table of, 251 

 of fatty acids, 257 

 of proteins, 258 



orientation of water around ions, 258 

 primary, definition of, 250 

 role in ion-ion interactions, 250, 272- 

 274 



secondary, definition of, 250 

 Hydrocarbon chain, 

 bond angles, in, 240 

 configuration of, 235 

 interactions between. 300 



Hydrocyanic acid, see also Cyanide 



dispersion electrons of, 225 



molar refraction of, 225 



optical constants of, 225 



polarizability of, 225 

 Hydrogen. 



dispersion electrons of. 225 



energy constants of, 237 



energy curve for interaction, 236 



molar refraction of, 225 



optical constants of, 225 



orientation on interaction energy, 241- 



242 



polarizability of, 225 

 Hydrogen bonding, 214-217 

 Hydrogen sulfide, 



dispersion electrons of, 225 



molar refraction of, 225 



optical constants of, 225 



polarizability of, 225 



Hydro([uinone, effect of pH on reactivity, 

 734 



Hydroxylamine. 



inhibition of catalase, effect of temper- 

 ature on, 755-756 



reactivation of cholinesterase inhibited 

 by TEPP, 630, 636 



of cholinesterase inhibited by car- 

 bamylating agents, 634-636 



Hydroxyl group, 

 bond angle in, 240 

 configuration of, 235 

 dipole angle of, 222 

 dipole moment of, 222 

 dispersion energy in hapten-antibody 

 reactions, 278 

 hydration of, 258 



interaction with cholinesterase, 290-291 

 molar refraction of, 222 

 van der Waals radius of, 234 



/S-Hydroxyphenylalanine, inhibition of 

 phenylalanine utilization in E. coli, 

 498. 500 



p-Hydroxyphenylpyruvate oxidase, sub- 

 strate inhibition, 112-114 



/3-Hydroxysteroid dehydrogenase, 

 complex of steroids and DPN, 299 

 substrate inhibition. 111, 121-122, 128- 

 130 



Hypothermia, effects on response to 

 anoxia. 780-782 



I 



Inactivation, 

 of enzymes, 



effect on rate of inhibition, 561-569 

 progressive during inhibition, 98-100 

 of inhibitor, progressive during inhibi- 

 tion. 100 



Index of fit, applied to enzyme inter- 

 actions, 303 



3-Indolepropionate, inhibition of ci-chy- 

 motrypsin, 

 effect of ionic strength on, 836 



Induced polarization, definition of, 217 



