Contents 



XI 



Calcification 497 Attrition 



Eruption 497 



497 



Chapter 8. Skin and its Derivatives 



BY MARY E. RAWLES 



Introduction 499 



Origin of the Skin 499 



Regional Specialization of the 

 Skin 504 



Integumentary Patterns 512 



Conclusion 516 



499 



SECTION VIII 



ENERGY EXCHANGE AND ENZYME DEVELOPMENT DURING 

 EMBRYOGENESIS 



520 



BY E. J. BOELL 



Introduction: Energy Require- 

 ments of the Embryo 520 



Energy Release during Periods of 

 Reduced Oxygen Supply or An- 

 aerobiosis 522 



Respiration 523 



Energy Sources during Develop- 

 ment 533 



Respiratory Mechanisms 538 



Conclusion 548 



SECTION IX 

 ONTOGENY OF IMMUNOLOGICAL PROPERTIES 



556 



BY ALBERT TYLER 



Antigens in Development 556 



Development of Natural Anti- 

 bodies and of Complement .... 564 



Development of Antibody-Form- 

 ing Capacity 564 



The Concept of Natural Auto- 

 Antibodies 566 



SECTION X 

 ONTOGENY OF ENDOCRINE CORRELATION 



BY B. H. WILLIER 



574 



Anterior Pituitary-Thyroid Rela- 

 tions 574 



Anterior Pituitary-Adrenal Rela- 

 tions 585 



Anterior Pituitary-Gonad Rela- 

 tions 593 



Anterior Pituitary and Growth . . 600 



Islets of Langerhans 606 



Parathyroid Glands 611 



SECTION XI 

 THE DETERMINATION OF SIZE 



620 



BY N. J. BERRILL 

 Growth Rate 623 



Relative Growth 625 



