Index 



729 



Isolation of blastomeres, 318, 319, 

 320, 321, 323, 324, 325, 326, 

 327 

 of egg fragments, 319, 320, 321, 

 323 



Labyrinth (membranous), axial 



modification of, 417, 418, 



419, 420 



capsule formation of, 422-423 



Laminated structure of myelin 



sheath, 367 

 Larval molting, hormonal control 



of, 342, 343, 638, 641 

 Lateral line, 362 

 Learning, 384, 392 

 Lens, antigens of, 559, 560 



dependent differentiation of, 



404, 405 

 fiber formation in, 407 

 from "foreign" epidermis, 404, 



405 

 induction of, 308, 404-^07 



factors responsible for, 406 

 initial size of. 408 

 from iris border, 308 

 from iris epithelium, 411 

 regeneration of, 410-412, 690- 



693 

 reinforcing inductors of, 405 

 specific proteins of, 407 

 suture lines of, 407 

 Wolffian regeneration of, 410- 

 412, 690-692 

 Lens-inducing stimulus, nature of, 



406 

 Limb, 361, 362, 374, 381, 382, 

 392 

 abnormalities of. See Chondro- 

 dystrophy, Creeper fowl. 

 , "aneurogenic," 361 



control by spinal cord, 387, 



388 

 exchange of, 388 

 formation of, mesoderm in, 433 

 function of, defective, 387 

 movements of, 378, 384, 391 

 normal development of, 429- 



431, 436-437 

 regeneration of, 369 



in amphibians. See Amphib- 

 ians, limb regeneration in. 

 blastema in, 679, 680, 681- 



683 

 endocrines in. 686 

 epidermis in, 679-684 

 field of, 677 

 mesoderm in, 680-684 

 nervous system in, 685 

 phases in, 681, 683 

 in reptiles, 686, 687 

 size regulation of, 628 

 suppression of, 381 

 transplantation of. 368, 380, 382 

 to head, 386 



Limb area (disc), 431 



equipotentiality of, 433, 434 

 fate of, 431 

 location of, 432 

 potency of, 432 

 Limb bud, 358, 361, 380, 431, 432, 



433 

 Limb centers, disarrangement of, 



387 

 Limb muscle, transplantation of, 



384 

 Limb plexus, 358, 384 

 Lipid development in adrenal cor- 

 tex, 588 

 Liver, differentiation of, heart in- 

 ductor and, 456 

 extirpation effects of, 456 

 onset of function, 457 

 regeneration of, 456 

 Liver-pancreas, labile determina- 

 tion of, 456 

 self-differentiation of primor- 

 dia, 455 

 Localization of cytoplasmic areas, 

 316, 321, 322. 324 

 of heart, 440, 441, 442 

 Lytic agents, chemical nature of, 

 192, 193 

 function of, 194 

 of sperm, 192-193 



Maintenance and development, 



mechanisms of, 531, 532, 533 

 Malformations by chemical-phys- 

 ical agents, 242-243 

 origin of, 237-238, 242-243 

 Mammals, chemical teratogenesis 

 in, 702 

 erythroblastosis in, 702 

 hereditary malformations in, 

 700, 701, 702, 703, 704, 708, 

 710 

 limb-girdle development in, 



437-438 

 vitamin deficiencies as terato- 

 genic agents in, 701, 712 

 x-ray induced malformations 

 in, 701, 710, 715 

 Marginal plasma. 230, 233, 234 

 Marginal zone. 233, 234 



potencies of, 238-242 

 Matrix, 353, 358. 361 



colloidal, 352, 359 

 Maturation, 381, 382 

 of nerve centers, 383 

 of ventral horn cells, 382 

 Maturation divisions, 180-181 

 Mauthner's neuron, 377, 378, 379, 

 389 

 fibers of, 362, 363 

 M-cell region, explants from, 379 

 Medulla oblongata, 363, 375, 378, 



379. 387, 392 

 Medullary cells (CNS), move- 

 ment of, 373 



Medullary plate, induction of, 

 250-254 

 organization of, 252-254 

 Melanoblasts. See Pigment cells. 

 Melanophores. See Pigment cells. 

 Membrane, cell, 56-59 

 Mesoderm, neurula, 247-252 

 Mesonephric areas, position of, 



463, 464 

 Mesonephric potency, 464 

 Mesonephros, development of, 468 

 forming area of, 464 

 nephric duct effects on, 468 

 Metabolic enzymes and mental 



derangements, 388 

 Metabolic patterns, induction of, 



282-283 

 Metabolism of cell division. 110- 

 111 

 of cells, 70-88 

 in development, 83-88, 520, 



524-525 

 in differentiation, 331 

 invertebrate regeneration and, 



672 

 metamorphosis and, 646-647 

 regulation of, 83-88 

 Metamorphic mechanism, activa- 

 tion of. 653-656 

 in amphibians, 654--655, 657 

 in insects, 655-656, 657 

 Metamorphic stimulus, action of, 



644-653 

 Metamorphic transformation, ces- 

 sation of, 656-657 

 Metamorphosis. 381, 385, 389, 

 391, 631-663 

 in amphibians, 631-637, 647- 

 648, 649, 650, 651, 652, 

 654-655 

 anterior pituitary and, 574- 

 575, 635-637 

 of brain, 389 



cell size change in, 620, 621 

 hormonal mechanism of, 644. 



646, 653-656 

 in insects, 637-644 

 metabolism and, 646-647 

 pattern of, 650 



in amphibians, 650-652 

 in insects, 652-653 

 tissue response in, 647-648 

 sensitivity of, 649-650 

 specificity of, 649-650 

 Metanephros, correlations in de- 

 velopment of, 469, 706 

 Methods and techniques, appraisal 



of, 25-37 

 Microcephaly. 706, 714 

 Micromelia. See Chondrodystro- 

 phy, Creeper fowl. 

 Microphthalmia, 383, 711 

 Microsomes, 44, 521 

 Midbrain. 361, 374, 379, 380, 383, 

 385, 387 



