734 



Index 



Size of body, 128-129 

 of cells, 620-621 

 determination of, 620-630 

 of eye, 407, 408. 409, 628 

 Skin, 362, 363, 368, 385 



beginnings as integrated sys- 

 tem, 499 

 derivatives and, 499-519 

 epidermal ridges of, 510-512 

 functional differences of, 505- 



506 

 morphological patterns of, 512- 



513 

 origin of, 499-504 

 pigment cell migration into, 



503-504 

 pigmentation patterns of, 513- 



515 

 regional differences established 



early, 506, 507 

 regional hormonal response of, 



505, 506 

 regional specialization of, 504- 



512 

 source material of, 499-501 

 source of pigment cells in, 502- 



503 

 structural differences of, 504— 



505 

 See also Epidermis. 

 Skin ectoderm, local induction of, 

 499 

 polar organization of, 501- 



506 

 primordial capacity of, 500, 



501 

 specialization of. 501, 506 

 Specificity, 361-362, 384, 386 



in regeneration, 362 

 Sperm, agglutination of, 182, 185, 

 186, 187, 188, 189, 190 

 antifertilizin of, 189-191 

 lytic agents of, 192-193 

 Spermatozoa, senescence of, 182- 

 184 

 approach to egg, 181-182 

 Spina bifida, 372 

 Spinal action systems, 387 

 Spinal cord, 361, 362, 363, 367, 

 370, 374, 375, 378, 379, 380, 

 381-383, 387, 388, 392 

 central canal of, 371, 373 

 longitudinal pathways in, 360 

 regional differences in, 382 

 serial functional localization 

 in, 387 

 Spinal ganglion, 362, 372, 377, 



378, 380, 381, 383 

 Sponges, dissociation experiments 

 in, 668 

 ionic balance as factor in regen- 

 eration of, 672 

 Spongioblasts, 379 

 Stomach, 456 

 Stresses in medullary plate, 359 



Stretch of longitudinal fiber tract, 

 359 



of neural tube, 373 

 Stump. See Nerve stump. 

 Substrata, 348, 352 



orientation of, 352, 354, 359 

 Surface of axon, 361, 368 



of neural plate, 369, 370, 373 



contraction of, 370 



Surface tension, cleavage and, 



218 

 "Symbiotic" interdependence, 388 

 Symmetry, bilateral, 230, 231, 284 

 Sympathetic fibers, 370 

 Sympathetic ganglia, 372, 381 

 Sympathetic nervous system, 



adrenal medulla and, 592, 593 

 Sympathetic neurons, 382 

 Synaptic connections, 363 

 Synthesis of respiratory enzymes, 



543-545 



Tail, hereditary abnormalities of, 

 700, 701, 702 

 phenocopies of, 703 

 regeneration of, in cyclostomes, 

 675 

 in reptiles, 686, 687, 688 

 in teleosts, 675, 676 

 Tail bud, differentiation of, 249- 



250 

 Teeth. See Tooth. 

 Teleosts, cleavage in, 298-300 

 endocrines in regeneration of, 



685-686 

 regeneration of nervous system, 

 676, 677 

 related to stages, 676 

 of tail, 675, 676 

 sensitive periods for x-ray in- 

 duced abnormalities in, 713 

 twinning in, 711, 712, 713 

 Teleosts and birds, axis formation 

 in, 299-304 

 cleavage period in, 298-300 

 gastrulation in, 300-306 

 pre-cleavage period in, 297- 



298 

 progressive differentiation in, 

 297-314 

 Temperature as factor in inverte- 

 brate regeneration, 671 

 growth and, 628, 629 

 as teratogenetic agent, 701, 702 

 Tension, 352, 353 

 Teratogenesis, 237-238, 242-243, 

 699-719 

 abnormal initial stimulus in, 



706, 707, 708 

 abnormal responsiveness of tis- 

 sues in, 707, 708 

 abnormal tissue differentiation 



in, 708 

 carbohydrate metabolism in, 

 705, 706 



Teratogenesis, causal agents of, 

 700-703 

 arrest of development, 



703 

 chemicals as, 701, 702, 704, 

 705, 708, 712, 713, 714, 

 715 

 dietary factors as, 701, 704, 



705 

 environmental factors as, 



701-702 

 gametes, physiological con- 

 dition, 711 

 hereditary factors as, 700- 



701, 711, 712 

 insulin, 703, 705, 712, 713, 



715 

 irradiation, 701, 709, 710 

 overripeness of egg, 709, 



711 

 physiological deficiencies 



as, 710 

 pituitary deficiency, 710 

 retardation of develop- 

 ment, 704, 705 

 rubella, 702 

 storage condition of chick 



egg, 711 

 virus, 702, 714 

 vitamin deficiency, 701, 



705, 712 

 x-rays, 701, 709, 710, 715 

 classification of terata, 706 

 correlations in, 703, 706 

 degeneration (cellular) in, 702, 



709, 710 

 dosage effects on, 715 

 environmental factors in, 701, 



702 

 erythroblastosis and, 702 

 hereditary factors in, 700, 701, 



711, 712 

 persistence of normally degen- 

 erating structures in, 710 

 phenocopies in, 702, 703 

 recovery from teratogenic 



agents, 715 

 responsiveness of tissues in, 707, 



708 

 sensitive periods in, 702, 705, 



712-714, 715 

 specificity of chemical agents 



in, 714-715 

 supernumerary organs in, 707 

 Terminology, difficulties of, 29 



Roux and, 29 

 Terni, nucleus of, 378 

 Thyroid in amphibian metamor- 

 phosis, 631-635 

 criteria of activity of, 633 

 initial response to thyrotrophic 



hormone, 582 

 iodine concentration in, 634 

 onset of hormonal activity of, 

 575. 576 



