506 



THE BIOCHEMISTRY OF B VITAMINS 



Table 8. Dissociation Constants and Bacteriostatic Activity of N-Substituted Sulfon- 

 amides and Related Compounds 



Compound 



p-Aminobenzoic acid 



NMSulfanilylsulf anilamide 



Sulfanilylcyanamide 



N'-Ethylsulfonylsulfanilamide 



Sulfanilylglycine 



N'-Chloroacetylsulfanilamide 



3-Sulfanilamido-4-methylfurazan 



5-Sulfanilamido-3-methylisooxazole 



3-Sulfanilamido-5-methyloxadiazole 



IN^-Benzoylsulf anilamide 



4-Sulfanilamido-l,2,4-triazole 



2-Sulfanilamido-l,3,4-thiadiazole 



N^p-Aminobenzoylsulfanilamide 



N^-Acetylsulfanilamide 



Sulfanilylurea 



2-Sulfanilamido-5-methylthiadiazole 



5-Sulfanilamido-2-chloropyrimidine 



2-Sulfanilamidopyrazine 



4-Sulfanilamidopyrimidine 



Sulfadiazine 



2-Sulfanilamidooxazole 



5-Sulfanilamidopyrimidine 



3-Sulfanilamidopyridazine 



2-Sulfanilamido-4-methylpyrimidine 



5-Sulfanilamido-2-bromopyridine 



Sulfathiazole 



2-Sulfanilamido-5-bromopyridine 



2-Sulfanilamido-4,6-dimethylpyrimidine 



2-Sulfanilamido- 4-methylthiazole 



NMSulfanilylsulfanilamide 



3-Sulfanilamidopyridine 



4-Sulfanilamidopyridine 



N 3 -Sulfanilylmetanilamide 



Sulfapyridine 



2-Sulfanilamido-5-aminopyridine 



5-Sulfanilamido-2-aminopyridine 



2-Sulfamilamido-4-aminopyrimidine 



N^-Phenylsulfanilamide 



2-Sulfanilamidoimidazole 



N^m-Tolylsulfanilamide 



N'-p-Tolylsulfanilamide 



N^o-Tolylsulf anilamide 



N^-p-Aminophenylsulfanilamide 



Sulfanilamide 



N^Methylsulfanilamide 



N '-Furf urylsulf anilamide 



N^Hydroxyethylsulf anilamide 



N \ N L D imethylsulf anilamide 



Sulfanilylguanidine 



Sulfanilylaminoguanidine 



4,4'-Diaminodiphenylsulfone 



