INDEX 



Absorption of B vitamins, 



factors influencing, 344 



in animals, 343-345 



in plants, 336-337 

 Abundance of B vitamins, in whole or- 

 ganisms, 24 

 Acetaldehyde, formation of, 221 

 Acetate factor, 16 ff 

 Acetic acid, 



aerobic production of, 164 



as metabolic intermediate, 190 

 Acetic acid-lactic acid dismutation, 164 



hydrogen carriers for, 164 

 Acetoin, from pyruvate, 161 

 Acetylcholine, 39 



formation in nerve tissue, 106 



role in production of electrical energy, 

 237 

 Acetylmethylcarbinol, formation of, 221 

 Acetylphosphorylase, 191 

 Achlorhydria, 266 

 Acid phosphates, formation of, 195 

 Acid labile forms of pyridoxine, 37 

 cis-Aconitate, formation of, 195 

 Activated acetyl molecule, 190 

 "Active acetate," 190 

 Active forms of B vitamins (see coen- 

 zymes of individual vitamins) 

 Addisonian pernicious anemia, 415 



therapy, 415 

 Addison's disease, pigmentation in, 425 

 Adenine, toxicity of, 296 

 Adenosine diphosphate, 



as phosphorylating agent, 191 



from DPN, 134 

 Adenosine triphosphate, 



in biosynthesis of thiamine, 157 



in muscular contraction, 236 

 Adenylic acid, role in coenzyme forma- 

 tion, 117 

 Adermin, 652 



Adrenal cortical relationships, 381 

 Adrenal cortex, effect of pantothenate 



deficiency on, 380, 424 

 Adrenal hypertrophy, 382 

 Adrenalectomy, effects of, 425 

 Adrenaline, from DOPA, 181 

 Aerobic respiration, energy conservation 



in, 150 

 Age, effect on vitamin requirements, 265- 



266 

 Aged, vitamin requirements of, 266 

 Agenizing of flour, 297 



Alanine, relation to bacterial pyridoxine 



requirement, 184 

 /3-Alanine, 35 



from aspartic acid, 85, 181 



relation to pantothenic acid, 466 



role in biosynthesis of pantothenic 

 acid, 85 

 Alcohol, effect on B vitamin require- 

 ments, 276 

 Alcoholism, chronic, 



as genetotrophic disease, 433 



with nutritional polyneuritis, 400 

 Aldehyde oxidases, 148 

 Aldol cleavage, in glycolysis, 219 

 Aldolase, 188 

 Alkaloids, in plants, 336 

 Alloxazine, 143 

 Amides, formation of, 195 

 Amines, detoxification of, 106 

 Amino acid decarboxylation, pyridoxal 



phosphate in, 181 

 a-Amino acids, 



coenzyme activating, 174 



effect on choline requirement, 278 



effect on riboflavin requirement, 277 



folic acid in synthesis of, 201 



PABA in synthesis of, 201 



relation to bacterial pyridoxine re- 

 quirements, 184 



requirements for plants of, 316-317 



role of a-ketoglutarate in synthesis of, 

 232 



synthesis of aromatic, 195 



vitamins required for degradation of, 

 233 



vitamins required for synthesis of, 231 

 D-Amino acid oxidase, 147 

 L-Amino acid oxidase, 32, 147, 148 

 ;>Aminobenzoic acid 



analogues, 291, 484-486 



anti-pernicious anemia vitamin in uti- 

 lization of, 203, 207 



assay methods, 71-72 



biochemical function, 11-12, 469, 488 



biochemical interrelationships, 470 



biosynthesis, 89 



combined forms, 40-41 



deficiency, 429-430 



distribution, 18-19 



effect of species size on requirement 

 of, 323 



excretion of, 365-370 



725 



