732 



INDEX 



Glycolytic process — Continued 



mechanism, 218 

 Grave's disease, thiamine administration 



in, 381 

 Gray hair syndrome, 381 

 Green plants, 



as food source, 244 



B vitamin deficiencies in, 397 



B vitamin requirements of, 316-318 

 Growth, 



as criterion for vitamin sufficiency, 250 



effect of B vitamins on, 379 



"improvement" in, 250 



"increase" in, 250 

 Guvacine, 336 

 Gynecomastia, in malnutrition, 382 



Habits, effect on B vitamin requirements, 



282 

 Harden's coferment, 133 

 Heart action, effect of thiamine on, 384 

 Heat lability as applied to vitamins, 37 

 Heavy metal poisons, 153 

 Hematopoiesis, 202 

 Hemes, 716-720 (See porphyrins) 

 Hepatic fatty infiltration, 248 

 Heteroauxin, 294 



Hexonic acid, from carbohydrates, 223 

 Hexuronic acid, from carbohydrates, 223 

 High energy phosphate bonds, 101, 163 

 Higher animals, B vitamin deficiencies 



in, 398 et seq. 

 Histamine, formation of, 181 

 Histidine, 

 as single carbon unit donor, 198 

 histamine from, 181 

 Holoenzymes, 30, 109 

 formation of, 116 

 stability of, 117 

 Homobiotin, 468 

 Homocysteine, conversion to methionine, 



233, 234 

 Hormone-vitamin interrelationships, 380- 



384 

 Human experimentation, 

 bioassay methods for vitamins in, 252, 



254-257, 283 

 variables in, 249 

 Human tissue, distribution of B vitamins 



in, 26 

 Humans, 

 B vitamin requirements of, 326 

 table of daily dietary allowances for, 

 324 

 Humidity, effect on B vitamin require- 

 ments, 267 

 Hungers, specific, 260 

 Hydrases, 127 et seq. 

 Hydrogen, production of from pyruvate, 



163 

 Hydrogen acceptor, DPN as, 219 



Hydrogen carriers, for acetate-lactate 

 dismutation, 164 



Hydrogenation-dehydrogenation, in gly- 

 colysis, 219 



/3-hydroxy acids, dehydration of, 128 



L-Hydroxyacid oxidase, 148 



3-Hydroxyanthranilic acid, 287 



Hyperthyroidism, 

 symptomology of, 380 

 B vitamins in treatment of, 381 



Hypophysis, 380 



Hypoxanthine, formation of, 199 



Illness, effect on B vitamin requirements, 



271 

 Inactivation of B vitamins, 



enzymatic, 292 



in intestine, 337-338 

 Inactivators, natural, 292 

 Index of Carbohydrate Metabolism, 404 

 Indole, tryptophan from, 183 

 "Infantile pellagra," 407 

 Inhibition, 



competitive, 443 



determination of type, 452-453 



index, 445-449 



mass action effect in, 444 



non-competitive, 443 



of enzymatic action, 445 



"quadratic," 454 



reaction rates in, 450-451 



synergistic action of, 463 

 Inhibition analysis, 



application of, 464 



in assay development for unknown 

 factors, 473 

 Inhibitors, 



destruction of, 463 



mechanism of resistance to competi- 

 tive, 475-477 



natural, 292 

 Injury, effect on B vitamin requirements, 



272 

 Inositol, 



analogues, 291 



assay methods, 64-66 



biological activity, 712-714 



biosynthesis, 89 



combined forms, 38 



deficiency, 430 



distribution, 18 



effect of species size on requirement of, 

 323 



excretion of, 365 



extraction, 38-39 



formation from carbohydrates, 223 



in amylase, 10, 38, 106, 125, 218 



in phospholipides, 38, 106, 127 



inhibition studies on, 125 



inhibitory analogues, 714-715 



requirements, 326, 327, 328 



specificity, 712-714 



