INDEX 



735 



Nutritional viewpoint of meaning of B 



vitamins, 13 

 Nutritional polyneuritis, 400 

 with chronic alcoholism, 400 



Occupation, effect on B vitamin require- 

 ments, 267 



Occurrence of B vitamins, reason for 

 universal, 98 



"Old yellow enzyme," 32, 144, 150 



Oleic acid, 

 biotin in synthesis of, 173 

 sparing action on biotin, 227 



Ornithine, putrescine from, 181 



Oviduct hypertrophy, effect of stilbestrol 

 on, 383 



Ovoflavin, 669 



Oxalacetic acid, formation of, 221 



Oxidases, amino acid, 147-148 



Oxidation-reduction potential, effect of 

 ascorbic acid, 21 



Oxybiotin, 8, 545-550 



PAC, 192-193 



Pancreatic amylase, 38, 218 



Pantoic acid, 35 



from pantonine, 85 

 "Pantonine," 85 

 Pantothen-, 20 

 Pantothenic acid, 

 ^ analogues, 289 

 / assay methods, 56-59 



biological activity, 620-624 



biosynthesis, 84-86 



coenzyme (see coenzyme A) 



combined forms, 34 



conjugate, 192-193 

 „ distribution, 19-20 



effect of biotin on requirement of, 278 



effect of species size on requirement of, 

 321 



excretion, 365 



extraction, 34 



fecal content of, 259 



functions, 465-466 



inhibition of, 464 



inhibitory analogues, 624-648 



interrelation to /3-alanine, 466 



interrelation to aspartic acid, 466 



interrelation to nicotinic acid, 282 



interrelation to PABA, 282 



interrelation to desoxycorticosterone, 

 melanin, 381 

 , liberation by enzymes, 34-35 



metabolism, 362-363 



oviduct response to stilbestrol and, 383 



relation to plant growth, 86 



role in sterol synthesis, 230 



requirements, 326, 327, 328, 329 



sparing effect of fatty acids on, 227 



specificity, 620-624 

 ., structure, 7 



Pantothenic acid — Continued 



toxicity, 391 

 v universal occurrence, 19 



urinary content of, 259 



Pantothenic acid deficiency, 



adrenal hypertrophy in, 424 



biochemical nature of, 424 



symptomology, 423 

 Partial genetic block, 217 

 Pasteur reaction, 32 

 Pathological states, 



effect on B vitamin requirements, 271 



relation of B vitamins to, 431-433 

 Pellagra, 



causation, 409 



distribution, 408 



effect of tryptophan in, 615 



historical, 398 



in pigs, 412 



incidence, 398 



mental symptoms, 410 



pathology, 410-411 



role of sunlight in, 409 



symptomology, 409 

 Pellagragenic agent, in corn, 280, 294 

 "Pellagra-preventive factor," 407 

 Pentoses, 



from carbohydrates, 223 



mechanism of formation, 224 

 "Perleche," 406 

 Pernicious anemia, 



Addisonian, 415 



excretion of folic acid in, 571 



hematological response in, 416 



relation of folic acid to, 204 



symptomology, 415 



therapy, 415 



thymine, folic acid, vitamin B ]2 in 

 therapy, 416 

 Perspiration, B vitamins in, 269, 368-369 

 PGA, 39 

 pH, effect on sulfonamide activity, 502- 



505 

 Pharmacological action of B vitamins 



(see individual vitamins) 

 Pharmacological level, 377 

 Phenylethylamine, formation of, 181 

 Phlorglucinol-like compounds, formation 



of, 195 

 Phosphatases, 157 



Phosphate bonds, high energy, 101, 236 

 Phospholipides, 



choline in, 11, 39 



inositol in, 38 

 Phosphoroclastic reaction, 162, 335 

 Phosphorus retention, effect of androgens 



on, 381-382 

 "Phosphoryl-acetyl intermediate," 162 



end products of, associated with thia- 

 mine metabolism, 165 



