66 



BIOLOGIC BASIS OF SEX 



lie in the relations of the human X and Y 

 chromosomes and autosomes and the bal- 

 ance of their contained genes. Little or 

 nothing is known about how these factors 

 operate in the given situations. 



Acknowledgment. In formulating and 

 organizing the material on which this paper 

 is based I have been fortunate in the helpful 

 discussions and analytical advice contrib- 

 uted so generously by Doctors H. L. Cai'son, 

 K. W. Cooper, H. V. Grouse, C. W. Metz, 

 S. B. Pipkin, W. C. Rothenbuhler, and H. D. 

 Stalker, and others having primary research 

 interests in this field. To them, and particu- 

 larly to my research associates Doctors S. 

 T. C. Fung and Janice Stadler, our secre- 

 tary Gladys M. Dicke and to my wife, 

 ]\Iarie S. Gowen, I tender grateful acknowl- 

 edgment for their contributions to the manu- 

 script. Direct reference is made to some 300 

 investigations in the body of the paper but 

 the actual number, many of which could 

 equally well have been incorporated, that 

 furnished background to these advances is 

 much larger, more than 1600. To this vast 

 effort toward understanding the foundations 

 for sex we are all indebted. 



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