ACCESSORY MAMMALIAN REPRODUCTIVE GLANDS 



405 



solatcral or lateral prostate) and the rate 

 of Zn*^^ uptake decrease after gonadectomy 

 as does the secretion of citric acid and fruc- 

 tose (see Section II). 



Dorsal prostate. The epithelium in the 

 dorsal prostate of normal rats is columnar 

 or cuboidal depending on distention of the 

 alveoli; nuclei are basal and stain heavily; 

 there is cytoplasmic vacuolization which is 

 usually limited to the basal region (Koren- 

 chevsky and Dennison, 1935) . 



Brandes and Groth (1961) described the 

 ultrastructure of two different cell types 

 in the dorsolateral (or dorsal) lobe. These 

 types differ in the relation of cytoplasmic 

 matrix to endoplasmic reticulum. In both, 

 the matrix is moderatelv homogeneous and 



contains small particles, but in cell type 1, 

 the matrix appears as separate profiles and 

 the reticulum as membrane-bounded indi- 

 vidual cavities. In cell type 2, the reticulum 

 forms dilated membrane-bounded cisternae 

 which are intercommunicating and the cy- 

 toplasmic matrix is reduced mainly to thin 

 strands appearing isolated within the cis- 

 ternae. 



Gunn and Gould (1956a) reported a 

 zinc-negative histochemical reaction in the 

 epithelium of the dorsal prostate. Fleisch- 

 hauer (1957) observed a slight dithizone- 

 stain macroscopically, and in unfixed frozen 

 sections, individual groups of cells contain 

 the distinctive basal zinc-positive granules 

 that are characteristic of all epithelial cells 



...\ 



Fl(.i. li..'N. l;;il v,l,ii;,l |Mm-;;:h, n,uM,:,l in.ih. 1 ,1. r i ,, ,i i li i in . ,-i:i [ .1, . 2(;,()()(); 1 ),-| ll ( )ll's 

 chrome o^niic and hxatixi . Il;i>:il pari ot epithelial cell to show the character of the granular 

 component and ergastopla>iiiic -acs which are essentially equal in amount in this region. 

 Double basement membrane indicated by arrow. (From J. C. Harkin, Endocrinology, 60, 

 185-199, 1957.) 



