G. W. McCOY 



959 



are required on each lot of serum tested with an interval of at least twenty-four hours 

 between them. The serum under test should at least equal, in percentage of mice 

 protected, the control serum which is distributed for purpose of comparison. This 



TABLE VI* 



Anti-meningococcic Agglutination Test 



* The figures i, 2, 3, and 4 indicate the degree of agglutination. 



control serum is used at the beginning and at the end of each test. The group of eight 

 animals receiving the control serum and the culture should have some mortality, but 

 not complete, at each test, and the control mice which die should show pneumococcus 



TABLE VII 



Anti-Pneumococcic Serum Test* 



*S = Survived. 

 D = Died — the figure indicating hour of death. 

 Dose of serum = o.2 cc. intraperitoneally. 

 Dose of culture = o.i cc. intraperitoneally. 

 Samples i and 2 averaged better than the control, while sample ,•? was inert according to this test. 



septicemia on necropsy and culture. Animals dying from other causes are considered 

 as if not injected. Two sample protocols covering tests on commercial sera are pre- 

 sented in Table VII. 



