I034 TUBERCULIN AND THE TUBERCULIN REACTION 



The basis for tuberculin treatment is believed to lie in the exceptional sensitive- 

 ness of the tissue immediately around tuberculous lesions. This may be thrown into 

 focal reaction by the introduction of amounts of tuberculin too small to influence 

 tissues more remote from the lesion. Mild degrees of focal reaction influence healing 

 favorably. 











Fig. 8. — Proliferative glomerular lesions in kidney of hog one month after renal perfusion with a 

 suspension of tuberculin protein. 



Some of the anatomical manifestations of tuberculosis represent allergic reactions 

 of the sensitive tissues of the body to the specific protein of the spreading, sensitizing 

 agent, with the specific anatomical response to the multiplying bacillus superimposed. 

 Other pathological lesions in the tissues, non-tuberculous in character, may represent 

 the effect of the protein from bacilli killed off in the lesions upon more remote but 

 still sensitized tissues elsewhere. 



