I048 ORIGIN OF ANTIBODIES 



CONCLUSION 



In spite of the fact that the origin of antibodies has been investigated by so many 

 methods, both direct and indirect, the site of their formation is still uncertain. Ex- 

 perimentally certain organs, particularly the spleen, and certain cells, such as the 

 tissue phagocytes, seem to be more actively involved in the production of antibody 

 than other tissues. However, from the evidence at hand, it is possible that antibody 

 formation may be a widespread cellular function in which all the cells of the body 

 participate to some degree. 



