92 J- SAKURAI. 



HoC-NAgH, 

 OC-0 



Moreover, there is a complete parallelism between the two equations : 



HoC-NHsCl H,C-NH3 



1 =-11 +NH,C1 



OC-ONH, OC-0 



and 



HoC-NA-lioCl H.C-NAgH., 



"I ' -=11 + AgCl . 



OC-OAg OC-0 



The synthetic formation of anhydn^iis l)etaïn fi'om trimethyl- 

 amine and chloracetic acid (I.iehreich : Her., 2, 1()7[18(JU]) can be 

 expressed in a mannci- [»crfectly analogous to that indicated for 

 glycocoll : 



H.,C-C1 1I.,C-X(C113)3C1 HX-X(CH3)3 



I +2N(CH3),-: I '--II +N(CH,VIIC1. 



OC-OII ' OC-ON(CH3)3li 0(-0 



If, however, we attempted to represent the abcjve change in a manner 

 analogous to that by which the formation of glyc(Jcoll is usually 

 represented — 



H,C - iCl + ' CH3 iN(CH3)., H.,C - N(CH3)., 



I • - I +CH3CI , 



OC-OH OC-OH 



H,C-N(CIl3), 1-LÇ-X(C1I3),II 



I -> I 1 



OC— OH OC— 



we should misrepresent the actual fact, inasmuch as dimethyl-glycocoll 

 is thus made to be the product instead of betaïn, unless, indeed, -we 



