C)^ J. SAKURAI. 



the way commonly adopted in the case of glycocoll, we should have 



H„C-:CÏ + HiNH(CH,) HoC-XH(CH3) 



"I - I +HC1, 



OC-OCA 0C-0C,H5 



ILC-NH(CH3) H.C-NH(CH3)(aH,) j 



"I -> I I 



oc-oaH, oc-o 



and in order to avoid the misrepresentation here involved that methyl- 

 ethyl-glycocoll is produced instead of sarkosine, we should have to 

 make an assumption similar to that made in the case of betain, an 

 assumption which is not supported by facts. 



It is, then, thnt property, characteristic of the class of compounds 

 under consideration, of producing internal ammonium salts, which 

 alone can satisfactorily explain the mode of formation of sarkosine 

 and betnïn. Tliis consideration gives a fresh confirmation of the 

 correctness of the closed formula for glycocoll, unless we disregard 

 the evident analogv wliich exists between it and its methyl 

 derivatives. 



The mode of formation of hippuric acid by the action of benz- 

 amide upon chloracetic acid has also to be represented in a manner 

 analoofous to that above advanced for 2'lvcocoll and its methvl dériva- 

 tives, thus : 



H«C-C1 HoC-NH^.COCeHs.Cl 



I + NH.COCJi, = I 



OC-OH ' OC-OH 



H.C-NHo.COCeH, 



= 'i 1 + HCl . 



OC - 



This way of regarding the formation of hippuric acid makes it also a 

 ring compound, a conclusion which is not contradicted \y\ facts ; on 



