10 



18 9 8 



30. FOWLER, G. Re 



The use of animal toxins In the treatment of inoperable malig- 

 nant tumors 



Amo Jo Med, Scl. Il6:l6l-l62, I898 



The author presents a review of the use of bacterial toxins 

 in the treatment of neoplasms. Among the reports discussed 

 were those of regressions after accidental infection with ery- 

 sipelas and after use of the septic products of the causative 

 streptococcus. The value of mixed toxins of erysipelas and 

 B. prodigiosus in the treatment of malignancies was assessed. 

 The rationale for the action of Streptococcus eryslpelatis and 

 its toxin is presented. Possibility of new applications of 

 this type of treatment lies in the suggested use of the serum 

 of animals infected with Str, eryslpelatis , of the venom of the 

 cobra capello, and in induced suppuration in malignant growths, 



- 1 9 3 - 



31, MACPAYDEN, A. 



Upon the immunizing effects of the intracellular contents of the 

 typhoid bacillus as obtained by the disintegration of the or- 

 ganism at the temperature of liquid air 



Proc, Roy, Soc , (London) 71:351.' 1903 



A method for the fractionation of bacterial cellular components 

 is briefly described, 



- 1 9 6 - 



32, COLEY, W. Bo 



Late results of the treatment of inoperable sarcoma by the mixed 

 toxins of erysipelas and Bacillus prodigiosus 



Am, J, Med, Sci. 137; 376-78, 1906 



The author reviews his work on the treatment of inoperable neo- 

 plastic growths through use of living cultures of Str, erysipelat 

 and its further development in the combined or mixed toxins of 



