20 



- 1 9 1 5 - 



all cases Included: Proof by microscopical examination; pri- 

 mary or recurrent inoperable sarcoma; treatment period three 

 weeks or longer; no other therapy given during mixed toxin 

 treatment. Cases were divided into six groups on the basis of 

 response to therapy. Twelve patients received no benefits 

 from therapy; 5 experienced some softening of the neoplasm 

 but no regression; 20 sarcomas disappeared and regrew after 

 some months; growths disappeared, but metastases were seen 

 later in 10 patients. Some diminution of the size of the 

 sarcoma was seen in 14 patients. The 73 patients for whom 

 apparent cures were obtained justify the use of the toxins 

 in these inoperable cases. The greatest percentage of cure 

 or amelioration was noted in the small round cell type of 

 sarcoma. In a few patients, striking relief from pain was 

 achieved . 



61 o LUDKE, H. 



Die Behandlung des abdominal-typhus mit intravenosen Injektionen 

 von Albumose (Treatment of abdominal typhus through intravenous 

 injections of albumose) 



Munch, med. Wchnschr. 62:321-323, 1915 



Deutero-albumose produced a febrile response when injected intra- 

 venously in treatment of typhoid . Pyrexia might be caused by 

 action of this primary cleavage product of albumin or outside 

 contamination of the solution by pyrogen-yieldlng organisms. 



1916- 



62, BIELING, R. 



K, 



Untersuchungen uber die veranderte Agglutininbildung mit 

 Ruhrbacillen vorbehandleter kaninchen (Research in the changing 

 agglutination picture in animals previously treated with colon 

 bacilli) 



Ztschr. Immunitatsforschung, u, Exp, Therap, 28:246, I9I6 



The agglutinins increased when previous immunization with colon, 

 dysentery or diphtheria bacillus preparations preceded in- 

 fections, such as typhoid. 



