23 



- 1 9 1 7 - 



resists boilings Tryptlc digestion, alcohol, acetone or ether 

 precipitation do not change its properties. In animals and 

 in humans, experimentally or accidentally infected with the 

 pneumococcus^ a similar or identical substance appears early 

 in the disease process. In blood and urine the specific pre- 

 cipitin reaction may have diagnostic importance, 



70, DUPLAN 



Les colloides et le colloidotherapie (Colloids and colloid 

 therapy) 



Rev, Int. med, chir, 28s 46-49, 1917 



Administration of colloidal toxic bacterial substances during 

 septicemia activates leukocytosis^ both genesis and migration. 

 The osm.otlc tension of the white cells is reduced after phago- 

 cytosis of these colloidal toxins; disintegration of the leuko- 

 cyte is thus hastened. In the circulation the liberated nucleic 

 acids initiate general systemic changes, 



71c HOLLER, G, 



Beobactungen uber die Wirkungsweise parenterale einverleibter 

 Proteink^rper zu therapeutischen Zwecken (Observations on 

 the mode of action of parenterally administered protein for 

 purpose of therapy in infectious diseases) 



Med. Klin, 13;1038-104l, I917 



The death rate in typhoid was reduced to 0,5^ and the average 

 duration of fever to 10 days when a 10^ solution of deutero- 

 albumose was injected in very minute doses once or twice 

 daily. Therapy should be continued until defervescence is 

 well-established , 



72, KIBLER, C, S, and McBRIDE, L, P, 



Intravenous injection of typhoid vaccine 



J, Infect, Dis, 21sl3-20, I9I7 



Intravenous injections of typhoid vaccine were administered to 

 six patients with typhoid fever and to one normal individual. 

 Temperature changes, leukocyte counts, agglutinin and opsonin 

 titers, blood pressure variations and coagulation time were 

 recorded. In both ill and normal patients, chills followed 

 immediately, accompanied by hyperpnea and, in some instance^. 



