38 



- 1 9 2 5 - 



111. MENTEN, M. L, and MANNING, H, M, 



Relationship of enteritldis - paratyphoid B infections to hyper- 

 glycemia in rabbits 



J. Infect. DiSo 37:400-410, 1925 



Rabbits were subjected to adverse environmental conditions for 

 one year. During this period all blood sugar changes were 

 recorded. Bacterial cultures were made of heart blood and organs 

 of all animals dying or killed within stated periods. Agglu- 

 tination tests with antisera obtained by rabbit inoculation with 

 these isolated bacteria followed; all organs were examined. In 

 addition the effects produced by both killed and living bacteria 

 were observed in the rabbit and dog^ 



A general seasonal variation in temperature was noted; the blood 

 sugar levels were found to be in reverse relationship to temper- 

 ature. Hyperglycemia was seen in cold weather. Most marked 

 hyperglycemic values were found after spontaneous infection with 

 enteritidis-paratyphold B groups. Hydropic degeneration of the 

 islets of Langerhans was noted only in prolonged hyperglycemic 

 conditions. Blood changes and histologic alterations were simi- 

 lar regardless of whether or not the injected organisms were 

 viable. The dog exhibits a natural resistance to the organisms 

 used in the study. 



112. MULLER, E. P. 



The involuntary nervous system: An important factor in the 

 body's resistance 



Arch, Int. Med. 35:796, 1925 



The theory is presented that the route or site of injection and 

 not the substance injected produces the phenomena seen in paren- 

 teral therapy. Dilution in peripheral vessels alters the 

 leukocyte concentration. An overbalance of parasympathetic 

 tonus follows with stimulation of myeloid tissue. This may 

 be the result of kinetic response of the involuntary nervous 

 system. Intradermal water, milk or salt solution (or air) caused 

 rapid leukopenia and a high concentration of leukocytes in the 

 liver. Peptone injection produced a migration of leukocytes 

 away from the periphery toward organ storage centers. 



113. PRIBRAM, B. 0. 



Proteintheraple und chirurgische Therapie des Magen-und-duodenal- 

 geschwurs (Protein therapy and surgical treatment of stomach 

 and duodenal ulcers) 



