48 



-19 2 7- 



143. VON EULER, U. 



If 



Uber Hyperadrenallnamie bel Pleberzustanden (On the Increased 

 blood adrenalin in fever conditions) 



Pfluger's Arch. ges. Physiol. 217:699-716, 1927 



- 1 9 2 S - 



144. ALLEN, A„ W. and SMITHWICK, R. H. 



Use of foreign protein in the treatment of peripheral vascular 

 disease 



J, A.M. A. 91:ll6l, 1928 



Typhoid vaccine, containing 125 to 300 million bacilli per dose, 

 was used in the treatment of Buerger's disease, in gangrene of 

 arteriosclerosis and simple vasomotor types of vascular occu- 

 lusion. The result of this treatment was most promising. It 

 is believed that tht benefits are chiefly derived from vaso- 

 dilatation, which brings relief of vasospasm and increases 

 capillary circulation. 



145. BORCHARDT, W. 



Zur Physiologic des Piebers Uber die Bedeutung von Schildruse und 

 Nebennieren fur das Pieber (Physiology of Pever. On the impor- 

 tance of tbyroid and adrenals in fever) 



Arch. Exp. Path. u. Pharmakol, 137:45-70, I928 



In an exhaustive study of the fever produced by bacterial, chem- 

 ical and mechanical stimulation of the midbrain, a primary 

 action upon the heat centers was noted. This can be delayed 

 by denervation of the liver. The presence of thyroid and adrenals 

 is important. The adrenals are not necessary to fever production, 

 but after removal, susceptibility to fever is increased. However, 

 no rigor follows when adrenals are removed. When adrenals 

 are intact, puncture of the heat center of the brain alone leads 

 to marked leukocytosis. 



