50 



-19 2 8- 



150. HESSE, E. and TAUBMNN, G. 



Untersuchungen uber das Fleber nach Heulinfus (Inquiry Into fever 

 after hay Infusion) 



Arch. Exp, Path, u, Pharmakol, 136:239-256, I928 



Extracts of decomposed hay, injected parenterally, caused 

 temperature increases. Analyses of these 'pyrogens' revealed 

 that humic acid was present. Like the humic acid from turf 

 and peat, it produced fever and leukopenia. 



151. KUTNEZOWSKY, N. 



Uber die Einfluss lokaler thermischer Reize auf den Speicherungs- 

 prozess in den Lymphknoten (The influence of local hyperemia 

 upon the storage process in lymph nodes) 



Ztschr. ges. Exp. Med, 62:44-61, I928 



In the stimulation of the reticuloendothelial system, the 

 route of introduction of various substances may be of great im- 

 portance. Storage of substances directly introduced into the 

 blood stream takes place in the reticuloendothelial cells of the 

 blood vessels; if the material is introduced into the lymph 

 gland, storage occurs in the cells of the lymph nodes. When 

 colloids are injected subcutaneously, storage is seen in macro- 

 phages of the connective tissue. It is possible to influence 

 the character of distribution of colloids through local hypere- 

 mia; storage thereafter takes place much earlier and in larger 

 amounts than is seen in unstimulated tissue. Heating of the. 

 lymph nodes before injection of a dye hastened the rate of 

 storage. 



152. SHWARTZMAN, G. 



Studies on Bacillus typhosus toxic substance I. The phenomenon 

 of local skin reactivity to B. typhosus culture filtrate 



J, Exper, Med. 48:24?, 1928. See also: Proc. Soc. Exper. Biol. 

 Med. 25:560, 1928 



Toxic filtrates were obtained from tryptic digest broth cultures 

 of E. typhosa strains. In rabbits intracutaneous injections of 

 a sensitizing dose, followed in 24 hours by a provocative in- 

 jection, produced hemorrhagic -necrotic skin lesions at the site 

 of the initial injection. From 78 to 79 per cent of normal 

 rabbits were sensitive to this reaction, which was not dependent 

 on the amount of filtrate used. No relationship was shown 



