54 



- 1 9 3 - 



Dermat, Ztschr. 60:404-4l2, I93O 



Specific vaccines were added to pyrlfer and administered to 15 

 patients with gonococcal Infections, The treatment was success- 

 ful for 73.3 per cent of the group, Pyrlfer alone. In dosages 

 calculated to Increase the body temperature to 40° C, brought 

 relief to 34,8 per cent of the patients In a second group,, The 

 values of adjuvant therapy are discussed, 



162. HARRISON, P. C, TARR, H. L. A. and HIBBERT, H, 



Factors relating to carbohydrates and polysaccharides, XXXIIIo 

 Synthesis of polysaccharides by bacteria and enzymes 



Canad, J, Res, 3:449-463, 1930 



163, KRUIffiRUCH, 0, 



Pyrlfleberhandlung bel leulschen Nervenkrankhelfcen (Pyri(fer)- 

 fever treatment In neurosyphllltlc conditions) 



Deutsche Med. Wchnschr, 56:2170-2173, 1930 



A preparation produced by Rosenberg of Freiburg (Pyrlfer) has 

 been used for therapeutic fever production in the Psychiatric 

 and Neurologic disease Clinic of the University of Gottingen. 

 As prepared from the killed bacteria of the colon group found 

 in milk, pyrlfer gives rapid elevation of temperature, occa- 

 sionally chills, and a strong leukocytic response. It is utili- 

 zed in seven different strengths containing from 50 to 5OO million 

 bacterial 'units' and is usually administered intravenously, 

 although more protracted fever follows intramuscular injections. 

 Leukocyte values rise to 20,000 or 25,000 total counts, with 

 neutrophils of Immature type accounting for tnost of the increase; 

 lymphocytes are decreased in number. 



Eight of 13 tabetic patients treated with pyrlfer improved. 

 Paralysis with tabes is less favorably influenced than pure para- 

 lysis with neurasthenic complications. Optic atrophy may be 

 hastened by fever therapy. There is speculation as to whether 

 or not heightened blood circulation may be credited for the 

 benefits received from this type of therapy. 



