77 



- 1 9 3 5 - 



within 10 minutes after injection and persists until the fever 

 raaximum is attained. After sympathectomy, vasoconstriction is 

 noted in 50 per cent of animals and ^ in the majority of these, 

 delayed vessel constriction occurs, Inactivation of the 

 adrenals may abolish the early responses of the vascular sys- 

 tem. In the general peripheral vasodilation after febrile 

 maximal points have been reached, the sympathectomized ani- 

 mals show a similar delay in vessel dilatation. 



232. PINKSTON, J. 0.* 



Experimental fever in sjrmpathectomlzed animals 



Am. J. Physiol. 111:539, 1935 



Complete removal of sympathetic chains from the stellate to 

 the pelvic ganglia brings a profound delay in both the initial 

 febrile reaction and in the attainment of maximal temperature 

 levels. The fever curves are flattened. With splanchnic section 

 or adrenal inactivation only, the behavior of the curve in 

 Induced fever approaches that seen in the normal febrile ani- 

 mal, 



233. SHWARTZMAN, G. 



Hemorrhagic necrosis and regression of sarcoma l80 



Science 82:201, 1935 



The lethality of E. typhosa filtrates was much reduced when cer- 

 tain proportions of homologous antlsera were combined with the 

 material. Single intravenous Injections of either antlserum- 

 filtrate mixtures or filtrate alone were administered to sarcoma- 

 bearing mice. The marked reduction in lethality which followed 

 did not affect the hemorrhagic -necrotic action of the filtrates 

 on tumors. Regression was prompt when a mixture of 200 neutra- 

 lizing units of antityphoid serum was mixed with 300 reacting 

 units of E, typhosa . 



234. WALTER, C. W. 



Economical intravenous therapy. 



J. A.M. A. 104:1688-1790, 1935 



Physiologic reactions ranging from fever and chills to cyanosis, 

 diarrhea, nausea, vomiting and collapse have been seen after 

 intravenous infusions of saline solutions contaminated from 

 impurities in distilled water, chemicals rubber tubing and glass- 

 ware. While individual susceptibility, velocity of injection. 



