- 1 9 3 9 - 



280. GARDNER^ R. Ec, BAILEY, G. H. and HYDE^ R, R. 



Hemorrhagic activity of toxic carbohydrate complexes from bac- 

 teria on a transplantable rat tumor 



Am. Jo Hygiene 29Bsl-1^5 1939 



The theory has been presented that generalized vascular shock 

 following injection of bacterial filtrates or specific substances 

 initiates tumor hemorrhagic processes o Such materials were 

 injected into rats bearing transplanted Walker tumor No, 256, 

 all cutaneous^ and approximately 10 days old. Controls were used 

 for comparison.. Non-bacterial carbohydrates and a yeast were also 

 injected o 



The yeast carbohydrate produced acute systemic reactions and a 

 hemorrhage in tumors which differed from that occurring after use 

 of bacterial filtrates o A polysaccharide-free component of the 

 soluble specific substance from So enteritides also had activity 

 and produced a severe reaction. Most marked results were obtained 

 with fractions isolated from the cultures of enteric organisms, 

 particularly those endogenous in the rat. However, other bacteria, 

 including Ko pneumoniae , had distinct activity, 



281. HARKAVY, J, and ROMANOFF. A« 



Local hemorrhagic -necrotic skin reactions in man (Shwartzman 

 phenomenon) 



Jo Allergy 10;566y 1939 



A comparison is made between mechanisms of the Shwartzman and 

 Arthus phenomena, and three case histories are presented for 

 illustration. Each presented skin lesions fulfilling all criteria 

 for Shwartzman reactions. The provocative factor which precipi- 

 tated lesions may be either a parenterally introduced antigen 

 from a bacterium or a product derived by an interaction between 

 an injected foreign protein and a preformed homologous antibody. 



282. IVANOVICS^ Go 



Chemische Untersuchungen liber de Polysaccharide des Milzbrand- 

 bacillus (Chemical studies in the polysaccharides of the anthrax 

 bacillus) 



Zentr, Bakto parasitenk, I, Abt„ l4ifj 2^4-246, 1939 



The water soluble precipitate produced after concentration and 

 purification of a culture of avirulent anthrax bacilli contained 



