101 



-19^0- 



the pyrogen Is not a polypeptide or an organic base. It is in- 

 soluble in fat solvents and not reduced by common hydrolytic 

 enzymes. Stability during autoclaving or treatment with strong 

 acids has been confirmed = It is divisable by specific precipi- 

 tants and adsorption agents, but is non-dialyzable, 



299. DE RENZI, S. and GRASSELINI^ A, 



Blood sugar in provoked hyperthermia (Translated Title) 

 Bollo soc. ital. biol, sper, 13; 802-803;, 19^0 



Hyperthermia induced by injection of killed bacteria increased 

 the blood sugar in both normal and diabetic individuals. Glucose 

 or galactose administered during fever brought blood sugar to 

 peak levels. During hyperthermia^ adrenalin and insulin produced 

 only insignificant changes in blood sugar o 



300. EHELSON, L, M. 



The inability of desoxycorticosterone acetate to protect the 

 adrenalectomized rat against typhoid vaccine. 



Endocrinology, 27:340, 19^0 



Since adrenalectomized animals are protected against typVioid 

 vaccine by cortioo-adrenal extracts, it was of interest to note 

 whether synthetic cortlcoids were equally efficacious, Wistar 

 rats vjere' adrenalectomized, and on the day after operation were 

 given corticosteroids; 20 rats were given 2 mg. of desoxycorti- 

 costerone acetate daily; 20 rats were given 2 cc of adrenal 

 cortex extract daily; ^■ rats v/ere given 4 mg<, of the syrithetic 

 daily. After 5-10 days of such treatment, typhoid vaccine 

 was given Intraperitoneally in doses varying from 0.5 to 0.8 cce 

 Treatment with adrenal substance was continued in those animals 

 that survived an observation period of 3 weeks, A few of the 

 anim.als in each group were given second vaccine injections 24 

 to 48 hours after the first. The synthetic product is unable 

 to protect the adrenalectomized rat against typhoid vaccine, 

 while the natural substance increases the resistance of such 

 animals. 



301. PREEIvIAN, G, G., CHALLINOR, So W. and WILSON, J, 



The use of a synthetic medium in the isolation of the somatic 

 antigens of Bact . typhimurium and Ba c t . typhosum. 



Biochera. J, 34:307-324, 1940 



