-- •' «-*»«-.*- 



113 

 -1^41- 



327« PASrtlCHA, C, Lo, MALIK, K, 3, flttd PAUL, Bo M, 



'^^Pyrogen' foimd In salines for Intravenous use 



Indian Med. Gaz, T6j216-218, 1941 



The soluble, heat -stable pyrogens which develop in pai»ent©»al 

 solutions through bacterial protein splitting are not easily 

 detected by permanganate titer. Only extreme eare in pro- 

 duction will prevent their appearance* but adsorption on char- 

 coal will ustuaXly remove all traces. 



328. SAHDERS, T, ««, 



Non-speciTio piMsein therapy In ocular disease 



J. Iowa Medo Soc, 31j51-54, 19^1 



Use of foreign protein therapy materially shortens the course 

 of noiny ocular infections and reduces permanent damage. It is 

 particularly effective in the treatment of ocular trauma. 

 Foreign protein therapy has been used, with more or less suc- 

 cess, in typhoid feveiP, pneumonia, puerperal fever, arthritis, 

 pelvic Inflammation, syphilis of the central nervous system, 

 other nervous disorders, multiple sclerosis, peptic ulcer, 

 dermatolog^Q eonditicms^ and in thxH>mbo -angiitis obliterans. 



329. &AKDWEXSS^ D» J«, SUGARMAK, M. H., PRl^DMAlf, M. H. P., 3AL7Z- 

 STEIN, H. C* and FARBMAN, A* A. 



The effect of «rlne extracts on peptic ulcer. An experimental 

 and clinical study i 



Am. Jo Dlges. Dlse 8g3Tl-382, 19^1 



Pregnancy turine and normal female urine appar^tly contain'' 

 a principle capable of exercising a beneficial effect on peptic 

 ulcer, as determined by the prolongation of life; spans of dogs 

 with experimental ulcerf, bylv the fibroblastic proliferation 

 and eplthelizatlon of ulcer craters. The action by which healing 

 is initiated appears to be concerned with suppression of se- 

 cretion, but healing appears through stimulation of fibroblastic 

 and epithelial cells and formation of blood vessels, as well. 

 When 14 patients with duodenal ulcer were given large doses 

 {30 to 40 mg«| oi normal female urine extract, Subcutaneously or 

 intramuscularly ft ftl1?e? injection of stimulating amounts of 

 hlBtamine^ total volame, but fjot acidity, of gitstpic secretion 

 decreased iter ©IsPonic peptic ulcer, a high peT*centage of re- 

 miaslojss ai%d total improvement was obtained. Relapses within 

 6 raonthe w#^ less fs^uently seen than with other medicaments* 



