X31 

 - 1 9 4 3 - 



}78. NECHELES, H. 



Depression of the stomach by nonspecific substances 



Proc. Inst, Med. (Chicago) 1^:345-346, 1943 



Prolonged depression of gastric motility and secretion was 

 possible through the injection, in the dog, of pyrogenic sub- 

 stances. The rectal temperature was unchanged. Pepsin, 

 enterogasterone and other depressants of gastric mdtility 

 may owe their effects to pyrogens. 



379. OTTENSOOSER, P. 



Sobre o plrogenlo (About pyrogen) 



Arq. biol, (Sao PauloJ 27:1-?, 1943 



Biological and chemical tests for the presence of pyrogens are 

 evaluated. The production of gelation in certain media, of 

 initial leukopenia and subsequent leukocytosis are characteris- 

 tic of bacterial pyrogens and pentose nucleotides. Pyrogen 

 may be produced In or related to nucleic cellular material. 



580. SHEAR^ M,,J,^ PERRAULT, A. and ADAMS, J. R., .TR . 



Chemical treatment of tumors. VI. Method employed in deter- 

 mining the potency of hemorrhage -producing bacterial prepara- 

 tions 



J. Nat. Cancer Inst. 4:99-105, 1943 



The bioassay method for determining the potency of bacterial 

 preparations for production of mouse tumor hemorrhage was found 

 to be inadequate for study of chemical and physical properties 

 of the active agent, A modified technique was adopted, sensi- 

 tive enough to enable distinctions between potencies to be made. 

 A standard material of determined potency was used for reference, 

 All contaminated tumor mash was discarded. Examination of the 

 interior of the tumor was performed. The mouse tumor unit was 

 defined as 'the amount of activity contained in the end point 

 dose' . 



