- 1 9 4 8 - 



study of patients before Institution of therapy and hospitali- 

 zation during treatment is advisable. 



517. BENACCHIO, Lo 



Contributo clinoco alia terapia vaccinicia endovenosa nelle 

 infezlone tifo -part if lone (Clinical contribution on intra- 

 venous vaccine therapy in typhoid -anti -typhoid infection) 



Gior, batteriol. e Immunol. 39:337-353, 19^8 



Forty-eight of 50 patients serologically positive for E. typhosa 

 received anti-typhoid vaccine intravenously, with recovery 

 following therapy considerably accelerated. The roseola herpes 

 disappeared soon after injection, the spleen diminished In size. 

 Leukocytosis and eosinophilia were observed during the treatment. 



518. BOQUET, P., DELAITNAY, A., LEHOULT, Y, and LEBRUN, J. 



Observation direct des reactions cutanees chez le lapin soumis 

 a I'epreuve d'une endotoxine typhique (Direct observations of 

 vascular reactions of the skin in the rabbit injected with ty- 

 phoid endotoxin) 



Compt. rend. Acad. Sci, 225:1193-119^, 19^8 



Injection of 6 to 8 mg, of purified typhoid glucido-lipido- 

 polypeptide antigen produces i^ithin 5 to 15 minutes constriction 

 and dilatation of the arterioles. This is the first symptom of 

 typhoid intoxication. Sympathetic innervation of blood vessels 

 does not prevent vascular reactions, 



519. CREECH, H, J., HAMILTON, M. A„ and DILLER, I. C. 



Comparative studies of the immunological and tumor-necrotizing 

 properties of polysaccharides from Serratia marcescens ( Bacillus 

 prodigiosu s) 



Cancer Res, 8:318-329, 19^8 



Comparative studies of the immunological, toxic and tumor-necro- 

 tizing properties of purified polysacchsrides obtained from cul- 

 ture filtrates of S. marcescens (P3, P5 and Pio) and those of 

 fractionation products from one straln'of the same organism are 

 prjc^ented. jminunisatic^n of rabbits folloKi^^ tiie inje-ction of 

 2 Big o of polysaccharide in divided cJoses over e period of two 

 weeksj the antisera was fractionated and studied serologically. 

 The lethal dosage was determined oj the mortality which resulted 

 from intraperitoneal injection of 100 to 2000 gammas of the 

 materials into normal mice. Tumor-necrotizing potency was 



