185 

 -19^8- 



528. HALL, V. E., GRANT, R. and FIELD, J. 



The Influence of substances affecting body temperature on thermal 

 polypnea 



Federation Proc. 7:^8, 1948 



The effect of substances which alter body temperature was deter- 

 mined on oxidative and glycolytic activity of cerebral cortex. 

 In the same studies, the respiratory response to heat (thermal 

 polypnea) was carefully measured. Thermal polypnea appears when 

 the rectal temperature of the rabbit has been increased about 

 2°C. by administration of typhoid -paratyphoid vaccine. When 

 panting is present before injection, it ceases within fifteen 

 minutes, and inhalation of 95^ oxygen (and % CO2) is not de- 

 pressed by vaccine. Normal respiration is observed in the 

 vagotomized rabbit. Polypnea may be provoked in the rabbit 

 by 3 niM per Kg, magnesium chloride at environmental temperature 

 of 20° Co or higher. 



529. HALL, V. E,, FIELD, J, and GRANT, R. 



The metabolic activity of the central nervous system as it 

 affects the thermostatic behavior of the body 



Memorandum Rpt , U, S. Air Force Air Materiel Command MCREXD- 

 b9b-113D, 19^, 99 PPc 



The effects of intravenous injections of typhoid -paratyphoid 

 vaccine in the rabbit and the cat were carefully studied by 

 collaborating investigators, and comparisons were made with those 

 noted after injection of a number of chemical thermogenic and 

 thermostatic substances. The site of action of pyrogenic 

 substances in the central nervous system, reactions after "shock" 

 doses and effects of T.P.T, vaccine on heat production, heat 

 loss and cold defense were ascertained and evaluated. 



While results were inconclusive and no proof of a thermal "trigger" 

 reaction in the central nervous system was forthcoming, the 

 report enumerates many interesting facts on calorogenesis after' 

 pyrogen administration and presents a series of methods well 

 adapted for use in such studies. 



530. HANSEN, J, L, 



Hyperthermia in association with shock 



Acta chir, Scand, 96:530-5^6, 1948 



Although the body temperature during traumatic shock is usually 



