195 



-19 4 9- 



554. BAKER, E. E. and GOEBEL, W. P. 



Studies on the enzymatic hydrolysis of the capsular polyr-L'i 



.1 saccharide of Klebsiella pneumoniae . Type B,, i:-.i- ..^..v ;.,y i-ie'i 



ds/-:.f:r:,_,:- '/■;::; " . - > "■ u'llv au030loincff 



sortBieloJ oU'ilv tioue to nor&os olcieqcdq-uxi sri^ 



cfD:'?'' ■"' ■ ~ ■ -■:~>VB 9ri:.J- no tb9bne,-tx9 



.Federation Proc. 8:400, 19^9 sew au^lv bsctssri lo 



.noissraio'l tne&neqsbnl ed cj aiseqqB ol 



3n^,V>'^,vv'' ' ■ .-...- .,.,,... r... ........r..-; oM 



bib 'An: enzyme capable of degrading capsular polysaccharide/ bns 

 -n was Isolated from soil bacilli, A motile, gram-negative ^on 

 spore-forming organism elaborates such an enzyme when it -Ifi 

 grovm in the presence of 0.1^ capsular polysaccharide otii-j':! 

 a medium containing ample sources of N but no growth factor. 

 The enzyme specifically hydrolyzes capsular polysaccharide 

 as shown by a change in the viscosity of the carbohydratei^f . T5cl 

 Loss of serological activity accompanies this drop in vis- 

 cosity. More than one enzyme may be Involved in the. phen-:^! 

 omenon, 



-o-ia aoY'icftrts 'oe.t.oe'ini rno -.. £Oin2,Lls-oX'^0!:iO lo , Im snO 



36 ilems 8.C E:--8ob ;::Mcfdfi'i srfJ al Q'sui^-a^qntsA nl asl's e beoub 



. ■ .s'yrusb wol s lo Tove'i bBOubo'iq oals , Xn 52.0 



555-.V :. BENVENUTl* M.? -,3:^0^' .iojIb s'TUod S o;t il xoods nssucf eiu:t&is 



-9b 4i o:^ c 'i' s bertoso'j ,.rjoY'::d.a^-9 beioe'lni: 8-H'J rao-il beiuo 



f;i,,>>'> Su,41i un tentative dl cura assoclati vaccino-siereterapial 



della pollomielite anterlore acuta (A trial of the treatr.r,\f 



^^oj meht of acute anterior poliomyelitis with-vaccine aia<3 jsersum 



rnuv..,.. therapy) ..,.,„..,,,„„..;.; j,;:* c'ly-vif',--:; b^^-Hjuo-ig cii:■'^:^^ 



be^o'^daeb -j-seri o;j- f)>iL!aoGxL5 ..soanoaaoi awiJrv erfd' besllBiJjjOif 



,■■■ ^.•. • , -HB a-ios^Jtcl- n-tnld-ulsasmori 



.. ,|Riv*. clin. Pediat,. 47:137-141, .1949^ ,o^q ^I.dr,SB-.i&^d '^^^^'^^l 



eeiD'Jsi^aii;o:y yd b'^vc'i-7c';-^b e'law a iilsrf.d'a ':.*'-'J enj biia arj'ily ssneuii 



A trial was made of the use of anti^rables vaccine with ma1;ernal 

 blood serum for five patients with severe or complete parsLlysis 

 r, of the lower extremities. The average dose was 3 ml, of .9 

 vaccine per day and total dosage was approximately 25 ml* Is 



Arrest of the paralysis was secured in all five cases. Re- 

 gression of the paralysis was succeeded by return of motility.. 8c'P 

 The sequelae were insignificant, 



•-,.■';■- - nfiXbf^fl 



