200 



- 1 9 4 9 - 



after injection of globulin fractions of mouse antiserum; the 

 latter was elicited by single injections of S. marcescens. At 

 a low globulin ratio (16-25) one fraction from P-10 preparation 

 afforded a high degree of protection against an LD-tq dose of S. 

 marcescens polysaccharide; a second preparation was less ef- 

 fective. 



567. CURRY, J. J. and SHAW, E, A. 



Continuous intravenous injection of typhoid vaccine in treat- 

 ment of certain ophthalmic diseases 



Arch. Ophthalmol. 42:123-125, 19^9 



Controlled hyperpyrexia through slow continuous intravenous 

 injection of a suspension of killed typhoid organisms (1 billion 

 per cc. and 1 cc. per liter of physiologic saline solution) pro- 

 duced excellent results for I7 patients with ophthalmic condi- 

 tions ranging from nonspecific iritis to syphilitic keratitis. 

 The risk of reaction is believed to be reduced considerably by 

 this method of administration. 



568. DAGLEY, S. and DAWES, E. A. 



Factors influencing the polysaccharide content of Escherichia 

 coli 



Biochem. J. 45:331-336, 1949 



Glucose, lactose and galactose increase the growth of E. coli 

 and increase likewise stored polysaccharide up to a maximum. 

 Fructose and mannose do not produce such increases in the poly- 

 saccharide. At a fixed sugar concentration, pH affected such 

 storage with glucose and galactose media but not with mannose 

 or fructose. Strain differences as to polysaccharide storage 

 were also noted. Polysaccharide content falls during the sta- 

 tionary phase of growth. The Sahayun method, when coupled with 

 the Hagedorn-Jensen test for reducing sugars, was not satisfactory 

 for the estimation of total bacterial polysaccharide. 



569. DELAUNAY, A., DELAIMAY, M. and LEBRUN, J. 



The mechanism of lymphocytic lesions provoked by epinephrine and 

 Salmonella typhi 



Compt. rend. Acad. Sci. (Paris) 288:139, I949 



Vascular disturbances, destructive to lymphocytes, and not 

 directly toxic effects upon nuclear or cytoplasmic components 

 characterize the effects of S. typhi endotoxin or epinephrine. 

 Hypodermic injection of lymphocytes with these substances into 

 the guinea pig provokes the same ' lesions ' as shown by lympho- 



