229 



-19 5 0- 



oxygen differences and vascular resistance were determined. 

 Paretic patients with the greatest amount of mental deterioration 

 had the lowest oxygen concentration in this area; with fever, 

 the optimum increase expected was approached. There was no 

 correlation between the degree of fever and O2 consumption. 

 Mean arterial blood pressure fell during fever. Patients with 

 asymptomatic neurosyphilis had normal oxygen consumption in the 

 afebrile state which was not altered during fever. In dementia 

 paralytica subnormal oxygen consumption was evident before 

 fever (2.1 cc per 100 Gm. per minute); during fever a 24^ in- 

 crease was registered (2.6 cc). It is believed that, in 

 the normal individual, cerebral blood flow and oxygen consumption 

 are likewise altered during pyrogen hyperthermia. 



654. HILL, A. G. S., DEANE, H. W. and COONS, A. H, 



Localization of antigen in tissue cells, V. Capsular poly- 

 saccharide of Frledlander's Bacillus , type B, in the mouse 



J. Exper. Med. 92:35-^4* 1950 



The fate of a capsular polysacchatide (that of Priedlander bac- 

 illus. Type B) was studied by means of homologous antibody lab- 

 elled with fluorescein. When injected intravenously into the 

 mouse, this acid polysaccharide is rapidly taken up by phago- 

 cytes In body tissues. It was seen in collagenous fibers of all 

 organs, in capillary endothelium, in the hepatic epithelium and 

 bile, the Juxtaglomerular segment of the distal renal tubule and 

 in a few casts. It had penetrated epithelium in uterine glands, 

 the hormone-secreting tissues of the ovary, the suprarenal corr? 

 tex, and lymph nodes and lymphocytes of the spleen. Synovial 

 membranes contained large amounts, "The polysaccharide was ^ 

 found in high concentration in pulmonary macrophages" after 

 Inhalation. 



655. HOWE, E. E. and TISHLER, M. 



U. S. Patent #2.532,^03, Dec, 5, 1950 



A method for removing pyrogens from aqueous solutions of the 

 acid salts of streptomycin. 



656. HOWIE, J. E. 



Pjrrexial treatment of ulcerative colitis 



The Lancet 25:827-8s8 (#6642), 1950 



The author presents a brief case report of a patient suffering 

 from ulcerative colitis for two years, who, after a course of 



