250 



-19 5 1- 

 (Translated Title) 



Seara medica 6:359. 1951 



The reactions characterized as pyrogenic may be controlled after 

 transfusion of blood by (1) discontinuance of transfusion, ad- 

 ministration of anti-febrile drugs, sedatives (2) substitution 

 of plasma and other equipment for transfusion. Calcium intra- 

 venously has been advocated as efficacious for these reactions as 

 has novaldin in one gram injections intravenously. "Prophylaxis 

 ot pyrogenic reactions Includes „. ,care in the collection and ad- 

 ministration of blood and a completely closed technie" . Pyro- 

 genic reactions may be actually pseudo pyrogenic reactions; the 

 ro±e 01 chilling and the use of frozen preserved blood are con- 

 ?pvn^!Si 5! ^"^52"' e^served an incidence of 3.9 per cent un- 



5?MHo5 ^^^^^Tf^^^^*^ ^^^^^ 2.069 transfusions, and these in- 

 cluded all reactions recorded, 



707. PISHGOLD, J. T., GRANT, R,, FIELD, J„ and HALL, V. E, 



?S^®2 consumptioa and glucose exchange in vitro of liver slices 

 irom febrile rabbits 



Am. J, Physiol, 166:113-120, I95I 



Sm!!?!!^ ^" liver function in fever may be caused by (a) heat pro- 

 me?abo?i^S°oJT^K"g r^!^°^^° process or (b) disturbance of the 

 t?n?P«i dT«S^-r''^°^?^''^*^ resulting in hyperglycemia and the 

 Tjypical diabetic syndrome, 



Sil??'?^«i.f?rr^*^''?J^^ measured in liver slices taken from ' 

 found ?hirio^^ sacrificed at the onset of the chill, it was 

 t?Dhoiri vLi?r? 5^2^"^^ ""^""^ present after pyrogen (typhoid para- 

 Union ^n^n^t^ !?^^ ''^''^ ^^^^ ^" untreated animals. The hydro- 

 IlLir.rnrf'rJ^'^" Zl^ ^ ^^°^°^ ^1^°^ si^°^ incubation of 

 levels \!n rliL $^^ ?'^^^'' consumption closer to normal 



Of fl^^r^ ^L } It of epinephrine could be measured at the onset 

 glucSIfwaS r^lL^S^ f ^^""^f °^ epinephrine, five times as much 

 no^alti^^n^ !5S?J''°'" i^^^"^ suspensions after fever as from 

 bo?S in thJ -:k.,??^^J^°" °^ epinephrine increased glucose values 

 no?Sal P,n?Lif ^^ *^^^"^ preparations and in those taken from 

 In^eL^iZL .T^^ suggestion is made that early hyperglycemia 

 SatrSom ?h^ iJf^^^^v,^'' ^""^ ^y ^ =^"^^^" release of ca?bohy- 

 that he^? n^n^.iJr'' ^^'^^"S^ sympathetic -adrenal stimulation, and 

 no? th?ou^n?"^Ji°" "?^u^^ mediated through nervous pathways and 

 not through direct peripheral action when pyrogens arradmiiLstered 



708. FITCH, E. M, J. and WASHRTTRMr a p I 



The effects of PYROMEN administered intravenously in subpyrexlal 



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I 



