^ "^1 9 5 2- 



740. CLEMENTE, C, D„ 



Penetrafciou of brain by r»gen«r«tlng peripheral nerv« fibers 



Anato Reco 112 §319* 1952 



When the tewportl branch of the facial iitfrvt of the cat was 

 severed and the atimp implanted iafe© the tewporal aortex, the 

 regenerating nerve fibers In anlnala r^elYlas PYROMIM* rapidly 

 penetrated the eortes? and blended with «erebral tisaue,, Such 

 regrowth was 8e«n aa early aa 30 day* after operation » Control 

 animals exhibited glial barrier* whloh |«»eYented blending of 

 regenerating nerve fibers with central nervou* parenchyma o No 

 blending was shown when cortisone was administered to cats with 

 peripheral nerve implantation in cerebral tissue » "The effects 

 of other steroids are being studied «" 



741. CLEMENTE, C» Do, SCOTT^ Do^ JRo, CHAMBBRS^ Wo Wo and WINDLE, 

 W » P» 



Structural and functional regeneration in the central nervous 

 system 



A, M.Ac Aroho Neurol « Psychlato, 1952 (in press) 



7^2. DOUGLAS^ Wo Wo^ and PATON^ Wo Do Mo 



The hypctherraic and antipyretic effect of preparations of 

 ACTH 



Lancet IsS^S^ 1952 



Preparations of ACTH lower body teraperature and delay the response 

 to pyrogens in norraal rabbits » Where pyrexia is established 

 after pyrogen adwlnlstration^ It is reduced by subsequent ad- 

 ministration of ACTHo This hypothermic effect has not been 

 previously reported. 



In these stuSies, pyrexia ^ indttcee though injection of 1 ftlcro- 

 gram per kllograia body weigfct of the eells of Proteus vulgaris ^ 

 was measuralUe in 20 to 30 minutes, ACTH,, oyrogirT-TFee^ was 

 injected in amounts of 1 or 3 units per kilogr-a® body weight 

 and the temperatar® rtdaetiom w^aswred*, Easl^ dos-e ciSidyoed the 



♦PIROMEN 



