30U 



Sl^igella dysenteriae , 



tolerance to toxic effects of, 



539, 5^0, 59S, 6G6 

 toxic and antigenic properties 



of fractions from, 5^6 

 type Z (Flexner), chemical 



degradation of, hlQ 

 type Z (Flexner), nature of 

 toxic component of, 683 

 significance in animal tissues, 



573 



specific, studies of fever in 

 sensitized animals, 77 



toxic, reticuloendothelial cells 

 reacting to, ^80 



typhoid, antigenic factor of 

 typhoid vaccine, 56 

 tolerance to action of endo- 

 toxins after typhoid and 

 paratyphoid fevers, G6G 

 tolerance to toxic effects, 

 in convalescents, 598 



AKTIHISTAMIIIES, 663, 



do not reduce toxicity of poly- 

 saccharides of S. marcescens 

 in mice, 6U2 



AIJTIHORMOKE : See Enterogastrone 



ARABINOSE,d-_,in fraction from 



culture of tubercle baci- 

 lli, 216 



ARGIWIlffi, toxic polypeptide 



gives color reaction for, 

 363 



AESEPIEKAIviiriE, therapy in neut'o- 

 ».■ syphilis, l^i-O 

 toxicity, intravenous sal- 

 varsan injs. without re- 

 actions, ^5 



relation to other forms 

 of injection fever, U9 



ARTERIES, disease: See Throm- 

 boangiitis obliterans 



ARTERIOSCLEROSIS, altered res- 

 ponse to tjTphoid vaccine 

 dioring massive salicylate 

 therapy, ^96 



in arterial hypertension, 

 therapy with pyrogen 

 (Pyromen) , 603 



therapy, irith foreign protein 

 (typhoid vaccine), ihh 



AririPYRETICS : See also Fever; Pyro- 

 gens; unde""" names of drugs 

 as, Acetanilid; Acetophenetidin; 

 Acetylsalicjrlic Acid; 

 Arainopyrene 



abolition of pyrogenic reactions 

 Tfith, 705 



depression of gastric sec- 

 retions with, without 

 fever, 685 



did not alter course of tolerance 

 to bacterial pjnrogens, ^70 



effect, modified by heat or cold 

 application to heat regula- 

 ting centers, 78 



testing, use of hay exts. infus- 

 ions in rabbits, 202 



APPARATUS, for intravenous and 

 subcutaneous use, 206 

 standardized, for prepn. of non- 

 pyrogenic fluids, 3^1 



APPETITE, in fever, ^h 



ARTHRITIS: See also Osteo- 

 arthritie; Rheumatism 

 acute, produced by intra- 

 articular inj. of typhoid 

 antigen, 5OO 

 rheujnatic polyarthritis, 



fever shock therapy in, 675 

 clironic, therapy, method for 

 controlled hyperpyrexia. 



359 



effect of artificially induced 

 fever on circ^^lation, 550 



in children, action of bac- 

 terial protein, question of 

 herpes, 166 



therapy, by intravenous inj. 

 of foreign protein 

 (typhoid vaccine), 66 

 subpyrexial doses of strep - 



tococciis vaccine, 212 

 with nonspecific protein 



(albumose, horse serum, bact- 

 erial proteins), 9^1-, 19I 

 with typhoid vaccine, 75, 82, 

 191 



