337 



INJECTIONS 

 intravenous 

 Proteus vulg. polysaccharide 



(Pyromen), 71? 

 •pyretamine' of Russo, U19 

 pyrogens, elimination, 20^4-, 206, 

 2k6, 3li^, 327, 370, 505, 599 



for inhibition of 



gastric secretions, 58O 



from typhoid vaccines, 



febrile response to, 585; loss 

 of activity, i+82, ij-93, 501, 

 610, 63i4- 

 Pyromen, in food allergies, 738 j 

 effect on adrenals and blood 

 components, 720 

 _S. marcescens , polysaccharide 

 from, effect on renal temp- 

 eratures (mice), U39 

 S^. typhosa , antigen, and pathology 

 after, 376 



endotoxin, vascular 



response in rabbit, 627 

 S. typhosa , toxins, 271 

 S. typhosa , vaccine; blood pic- 

 t\ire after, 619; cardiac 

 enlargement after, ^4-6 3; 

 fatality after, h26; neuro- 

 syphilis benefited by, 605; renal 

 blood flow after, 26U 

 typhoid -paratyphoid vaccine, and 

 other pyrogens, 579; thermostatic 

 behavior in body, 529; as 

 "pyrexin", 577; temperature in- 

 creases after, 270 

 use of rabbits for testing 



pyrogens in, 337 

 water for, nonpyrogenic, 20U, 246, 



505 

 bacterial filtrates, vascular shock 



after, 280 

 endotoxins of histolytic bacteria 



(in rabbits), 169 

 ext. of E. typhosa in rabbit, 



action on arterial pressure, 



476 

 polysaccharide, reaction of 



patients with malignant 



tumors to, 390 

 preparation, dextrose and saline 



solns. for, 206; safe sol., 2h6 

 pyrogens in injectable solutes, 



327, 505, 599; bio-assay accord- 

 ing to French Pharmacop . , 635 



elimination, 20U, 206, 246, 

 314, 327, 505, 599; ty 

 activated charcoal, 327^ 

 422; by ion exchange resin, 

 370 

 nature of, 700 

 technics of U. S. Pharmacop. 



test, 571 

 tests based on leukocytosis 

 of rabbit, 633 



for, 699 



pyrogens, prepn. of nonpyrogenic 

 saline fluids, 457, 459 

 reactions and preventions, 

 505, 652 

 site or route, not substance, 

 produce phenomena seen 

 in parenteral therapy, 112 

 subcutaneous, allantoin in 

 Ringer's soln., 4l0 

 ascorbic acid, 275 

 bactericidal activity 



following administration, 

 186 

 E^. coli vaccine in rabbits, 



273 

 hay exts. in rabbits for 



testing antipyretics, 202 

 Pyrotoxina bacterica , chemo- 



tactic reaction, 21 

 S^. marcescens polysaccharides 



in dog, 296 

 typhoid anaphylatoxin in 



rabbits, 51 

 yeast to produce fever, 



aspirin effects, 369 

 sub#patellar, of typhoid anti- 

 gen in rabbits, changes 



induced by, 5OO 



INSANITY: See also Dementia 



Praeccx; Mental Diseases; 

 Paralysis, General 

 manic-depressive, induced 

 fever and, 292 

 therapy with pyrifer, 217 



INSULIN, diminished inhibition 



to glycogen synthesis, 534 

 effect on blood sugar during 

 induced hyperthermia, 299 



on glycogen reseirves in 



liver, 273 



