FOErSACCKIRIDES 

 from Pneiimo coccus 



C, cutaneous and serologic reac- 

 tions, 2li8; effect of calcium 

 on flocculation reaction ivith, 

 3l5j precipitation of blood 

 protein vrLth, 322 



effect on capillary circulation, 

 362 



separated from proteins try 

 extg. with phenol', 309 



type I, fractionation and physical- 

 chemical studies, 512; type I 

 (and v.), improved method for 

 prepn, , 6k9 



type II and III, localization of 

 antigen in tissue cells, 6^8 



type IV, N-containing, specific 

 and nonspecific, 177 

 from Proteus vulgaris, 67, 693, 702, 

 709, 715, 728, 732, 75b, 773 



ACTH-like effect of fever in man 

 (l^,Tonen), 715 



chemical study, 773 



physiological action, 773 



serological study, I87 

 from Pseud omonas species, 1^81, 5^3 

 625, bl43, 655, 670, 671, 690, 

 691, 693, 702, 703, 70I4, 709, 

 728, 732, 735, 736, 7I4I4, 7ii9, 

 7514, 762, 773 

 from Salmonella species, erythrocyte 

 sedimentation rate increased 

 by, 611 



immunological relationships, 287 



lipid-protein complexes from, 61I, 

 773 



polar bodies of, 763 



toxins, from S. enteritidis , 617, 

 311; from S. typhimurium, prodn, 

 of pathologic changes, 297 

 from Serratia marcescens, action of 

 toxic doses on dog and guinea 

 pig, 39I4 



anaphylaxis not produced by, 395 



anoxia in tumor tissue, prodn. 

 by, 76b 



anticoagulant effect on normal 

 and thrombocytopenic plasma, 

 721, 71^3 



changes in adrenals of tumor- 

 bearing mice after, 522; de- 

 generative in tumor cells, ii85 



355 



chemical alteration of, 613, 

 773; by iodopolysaccharide in 

 tumors, ^hhl studied by 

 additions of radioactive I, 

 %^ 



chemotherapy of neoplastic 

 diseases, 672; See also: 

 Pyrogens, Sarcoma, Tumors ' 



comparisons of immunological, 

 toxic and tumor-necrotizing 

 properties, I18I4 



cytological effects on tumors, 

 l4i43, Ui;l4, 198, 6I42, 650, 76I4 



effect of detoxifying agents, 

 on toxicity, 6I42; of adrenal 

 cortex extracts combined irvith, 

 i486; of immunization on 

 lethality, 565; of storage 

 and freezing on properties, 

 519; of sublethal dosages, 

 396 



effect on blood pressure, in 

 tumor tissue, 372, 1436, 5l5, 

 770; systolic, 5l5; capillary 

 circulation, 1^36; on plasma 

 clotting, 721; rectal temp- 

 erature, Ii39; sarcoma, mouse, 

 372, I498, 6I42, 650, 76I4, 

 fractions, antigenic and 

 immunologic, 616 



hapten, antigen, site, 763 



histologic appearance of 

 tumor tissue after, ii56 



immunologic properties, lj8Ii, 

 519, 616; relationships, 

 between filtrates and Shear 

 polysaccharide, 1^05; of 

 anti-body-containing fractions, 

 52O; passive immunization 

 against toxic activity, 566 



iodinated, effects on carcinoma, 

 508 



nitrogen content, effect on 

 ttffliors, 330 



pigment elaboration a factor in 

 activitj'-, 562 



polar bodies as source of, 763 



preparation, 50I4 



pyrogen, active, from, 67lip 

 use as pyrogen, ii38 



reactions to injections of ■ 

 tumor-necrotizing prep- 

 arations, mice, I4O6J 



