PROSTIGIUNE, prodn. of continuous 

 gastric motility in dog, 355 



PROTEASE: See Enzymes 



PROTEINS: See also Albumin; Amino 

 Acids; Nucleoprotein; Poly- 

 peptide; Xanthoprotein; etc, 

 and derivatives, chemical nature 



of immune substances, 13ij 

 bacterial: See also under names of 

 bacteria, as Bacteria, coli 

 action on arthritis of childhood, 



question of herpes, l66 

 certain phenomena associated with, 



83 

 dialyzable product source of 



pyrogenic activity, 58 

 effects on eviscerated dogs, 130 

 extracts used in therapy of 



uveitis, 158 

 glutathione and ergothionine in 

 blood increased during pyrexia, 

 207 

 in therapy of arthritis, 9hi of 



dermatology, 95 

 influence of blood (cells, chemistry, 



volume, rate), 157 

 sensitivity in therapy of bron- 

 chial asthma with vaccines, 89 

 colorimetric tests for tyrosine, 

 arginine and histidine in 

 polysaccharide fraction of B_. 

 prodigiosus gave positive re- 

 sults, 372 

 component of antigenic conplex 

 of E. typhosum , 353 r °^ strain 

 of Typhoid bacilli, 331^ 

 decomposing substance, toxic prin- 

 ciple found in, i) 

 effect upon leukocytes, 137 

 fevers, (milk, casein, albumin, 

 edestin, hemoglobin), 107 

 pharmacology of, 175 

 theory of pathogenesis, 67 

 usual and unusual reactions to, 



190 

 toxic or dynamic, 126 

 foreign; See Protein, therapy; 

 Toxins; names of bacteria; 

 Typhoid, vaccine; etc, 

 fraction of B, dysenteriae pro- 

 duced hyperglycemia and leuko- 

 penia, 258 



357 

 heterologous, sensitizes certain 



cells of tenperature- 



regulating centers, 77 

 hydrolysates, casein, peptides 



produce fever, 769 

 — removal of bac- 

 terial pyrogens from I43I4 

 in blood: See Blood, proteins 

 in specific antigenic conplexes 



of Sh. paradysenteriae , i4l8 

 injections, thrombopenia of, II8 

 metabolism, 12I4 



influence of toxic substances on, 



125 

 nonr-diazable, polysaccharide 



fraction from S. typhimurium , 



pathologic changes in rats 



and mice, 297 

 nonspecific, (chemical and 



physiological mechanisms), 



228 

 bacterial, tuberculin reaction 



through, 15 

 poisonous, theory of patho- 

 genesis of fever, 67 

 polysaccharide- lipid-protein 



conplexes from Salmonella 



group, 611 

 reactions, lymph and serum ferments 



during shock, 68 

 requirements, minimal, of man in 



health and disease, 121^ 

 retains water in body, alimentary 



fevers, 17l^ 

 role in specificity of reaction 



to living or killed bacteria, 



209 

 solutions, cone, (serum, plasma, 



hemoglobin) reducing pyro- 



genicity, 509 

 split products, absorbable in 



digestive tract or intestines, 



126 

 basic cause of fever theory, 



in relation to immunity and 



disease, 57; pyrogen test, 



767 

 in therapy of eye inflammation, 



135 

 nonspecific protein therapy 



develops resistance to toxic 



or, 101, 102 



