372 



TISSUE: See also Cells: I'uscles; 



Nerves ; etc . 

 alteration dxn*ing fever in in- 

 fections and by hyperpyretics, 



122 

 anoxia, effect of bacterial endo- 

 toxins on carbohydrate metabolism, 



536 

 connective , endocrine and cellular 



response to admin, of bacterial 



p:>'rogen (Pyromen) , 688 

 mast cells, alteration induced by 



bacterial pyrogens, 678, 679; 



response to bacterial pyrogens, 732 

 plasma cells foimd in, 257 

 culture, sarcoma #37 in, effect of 



tumor-necrotizing agents (emetine 



HCl and polysaccharide S_. mar - 



cescens), k^Q, 'j6k 

 destruction, influence on toxicity 



in fever, 125 

 permeability, edema after tourniquet 



pressure caiised no increase in, 



k36 

 reaction to pyrogenic prepn. from 



Pseudomonas , 69I 

 scar, prevention: See Nerve, Piromen 



TOLSEROL, intravenous inj. diminished 

 reaction to Pyromen, 722 



Coley's (mixture of erysipelas 

 and prodigiosus toxins): See 

 Coley's Fluid 



extraction, pyrogens removed by 

 cyclic or heterocyclic acids, 

 with ETOH and BzOH, cooling and 

 filtration, 570 



link between toxic nucleoproteins 

 and complex antigens and 

 variants of bacteria, 14-12 



TRAUIIA: See also Shock, stirgical 

 injury to blood cells may release 

 pyrogens, explains fever 

 activity, il-27 



TREiroELElTBURG POSITION, in extreme 

 hypotension from pyrogens, 

 J+20 



TRICHLORACETIC ACID, extraction of 

 bacterial antigenic fractions, 

 301 

 extracts of bacterial prepns. 

 produce leiikopenia on in j , , 

 366 



TRYPANOSOMA nagana , toxin, effect 



after section of medial hypo- 

 thalamus in rabbit, 55 



TOURNIQUET, shock effect on peripheral 

 capillary circulation in un- 

 anesthetized mice, U36 



T0/G:NS: See also Bacteria; under names of 

 bacteria' as , Eberthella typhosa ; 

 Serratia marcescens ; Staphylococci ; 

 Typhoid: etc. 

 bacterial: See also Diptheria, toxins; 

 Tetanus . toxins chemical action 

 of, 58 



colloidal, admin, dxrring septicemia, 

 70 



effect on hunger and appetite in 

 fever, 7^.: on leiokocytes, 35; 

 on tumor hemorrhage prodn. , k33 



endotoxins of gram-negative bac- 

 teria, effect of sulfonamides of, 

 4ll+: temperature factors in action, 

 U13 ; partial, in protoplasm, 50 



reactions of mouse carcinomas to, 

 225; tumors, I98 



TRYPSIN, digestion, method for prepg. 

 antigenic fractions from B. 

 typhimurium and B. typhosum , 

 301 ; for antigenic substances 

 from typhoid bacilliis, 309 



TUBERCLE BACILLI, culture, anti- 

 biotic action of B. sub - 

 tilis and its secretion on; 

 also cultures of B. mesen - 

 tericus vulgaris , 119 



extracts from cultures com- 

 bined with bacterial pro- 

 teins, use in uveitis, I58 



fraction, chemical analysis, 

 216 



toxins, in liyperthermia, I8; 

 filtrate activity, 2^+5 



TUBERCULIN, allergy, 68I 

 polysaccharides, 7^9 



