(33 Art. l.-K. Fuji: 



tioii tu tlic iutervcils butwcen tliose and tho stimulas, so tluit tlie 

 discharges of tlie higlier orders chase the succeeding stimulus. At 

 •the instant at which one of the discharges of the higher orders just 

 comes at the j^rincipal discharge due to the succeeding stinuüus, 

 the height of the discharge must be increased. By this consider- 

 ation not only tlie tirst maximum of the fatigue curve may be 

 explained, Ijut its wave form may ho interpreted also. In the 

 case of muscle, ability for response of the higher order may l)e 

 observed in the so-called tetanic state which, in my opinion, is 

 caused by a series of responses successively evoked by the preced- 

 ing electric response acting as a stimulus on the tissue in a highly 

 excitable state. This view may be supported Ijy the fact that the 

 decrease of the proper period Avith the rise of temperatures follows 

 the same law as that of the increase of the speed of propagation 

 through the nerve. ''^ Then may not the same interpretation be 

 applied to the case of muscle ? Concerning this point further 

 investigation should be necessary. Here we describe this as an 

 interpretation wliich seems to he true in so far as our experiment 

 goes. 



Next we shall explain another form of fatigue oscillogram. 

 Oscillograms No. (*), No. 78 and No. 78' (Plate XXVI.) show such 

 experiments. From these oscillograms we see that, when the 

 fatigue advances, tlie modal latent period is prolonged and the 

 lieight of the discharge curve decreases. Oscillogram No. 7 (Plate 

 XXVII.) is an example in which the discharges appeared in a 

 . very complex manner. Perhaps the discharge was affected l;)y 

 the tertiary discharge belonging to the preceding set, but no 

 satisfactory explanation has l)een obtained. The following 

 , explanation looks somewhat prol)al)le. The discharges due to the 

 opening-stimuli at tirst appeared, then those due to the closing- 

 stimuli were superposed on their ascending branches, and finally in 

 the advanced stage of the fatigue, only those by the closing-stimuli 

 remained. For tlie sake of correctness of this consideration, it 

 must l)e assumed that the modal latent period belonging to the open- 



jDittler and Tichomirow. Pflüger Archiv, Bd. 125, S. 117. 

 ""'1 Dittler and Oinuma. Pflüger Archiv, Bd. 139, S. 293. 



