186 



WEEKS— HEREDITY OF EPILEPSY 



[April 19, 



and 26 or 21 per cent, are neurotic, while 46 or 39 per cent, were 

 apparently normal. 



This fitting confirms very closely with what might be expected 

 from the type simplex by nulliplex, indicating that the parents who 

 have been classified as duplex (normal) are really simplex, in that 

 half their germ-cells have and half lack the determiner for normality. 



Twenty of the normal parents had ancestors who showed some 

 mental or nervous weakness, this would justify their classifica- 

 tion as simplex. In 26 cases little is known about the ancestors of 

 the normal parent. The available information about three would 



^(g)^[T]-T-0 



v^ 



n1 (T)0(i)(5SD-r®l] ®on 



[sfs®^hH3~o 



13 5 6 2 



6 6 i 6 S~~^ 



Fig. 7. The central mating in this pedigree is that of an epileptic 

 woman, who descended from an epileptic father and has several defective 

 relatives, and a normal man, who comes from normal ancestors. There were 

 six children, two epileptic, and four neurotic. E, epileptic; F, feeble-minded; 

 /, insane; T, tubercular; B, blind; N, normal. Case 2,207. 



indicate that they are mentally normal. Judging from their off- 

 spring, we believe that subsequent data will show that these appar- 

 ently mentally normal parents descended from tainted ancestors. 



(Fig- 7-) 



Eleven matings of an insane and normal parent, resulted in 50 

 conceptions ; 10 died before 14 years of age, 7 are too young for 

 classification. Of the 33 remaining, 12 or 36 per cent, were epi- 

 leptic, 2 or 6 per cent, feeble-minded, 18 or 55 per cent, seemingly 

 normal, while i or 3 per cent, was neurotic. 



