I9I2.] 



STOCKARD— CONTROL OF DEVELOPMENT. 



197 



become white, this is transitory in most instances and the eyes finally 

 clear again and remain in a normal condition from then on. Most 

 of the specimens have fattened under the alcohol treatment. 



The matings have been made in such a fashion as to test several 

 questions. First, alcoholic males are mated with normal females, 

 paternal influence, the crucial test for the effect upon the germ cells. 

 Second, alcoholic females are paired with normal males, the maternal 

 influence plus the direct action on the developing embryo. Lastly, 

 alcoholic males and females are paired. 



The results of 40 such matings are shown in Table I. The 

 decided effects of the alcoholic treatment are seen when the records 

 are compared with those of the normal guinea pigs. 



TABLE L 

 Matings of Alcoholized Guinea-pigs. 



In the 24 cases in which normal females were mated with alco- 

 holic males, 14 gave negative results. Some of these probably 

 aborted early as the parents were all fertile and the female is apt to 

 eat the young before they have been observed when they are born 

 prematurely. Five of the matings gave stillborn young, in some 

 cases they were born a little before term. Litters were born alive but 

 the young died soon after showing many nervous symptoms, such 



