NINTH ANNUAL YEAR BOOK— PART IX 385 
While the cholera has worked disastrous results among the hogs, it 
has been under constant surveillance and at least one remedy has been 
found after years of study, which it is believed will relieve the conditions, 
and eventually immunize hogs from taking it. Dr. W. B. Niles, co-oper- 
ating with the government Bureau of Animal Industry, has experimented 
with what is known as hog cholera serum. The Bureau of Animal In- 
dustry has taken an active interest in the experiments, until now this 
serum has been practically adopted by the bureau as official. It is hoped 
that Iowa will follow the example of other states in providing for the 
manufacture or preparation of this serum after this formula, so that 
farmers and stock raisers of Iowa may obtain much needed benefit from 
its application to their herds. 
MALADIE-DU-COIT. 
Perhaps the most interesting and yet serious case coming to this de- 
partment, and related to the horse, has been that of Maladie-Du-Coit, 
which originated in Van Buren county. It has been fully determined 
that this disease, while of very rare occurrence, was one of the most 
destructive known to veterinary science. In this case, the malady origi- 
nated in a thoroughbred stallion, bought by a company of seventeen 
farmers in ^an Buren county, and this animal came from Columbus, 
Ohio, having been shipped under proper authority, as at the time, being 
free from disease. The price paid for this horse was $3,000. Following 
is a photograph of the horse known as Marquis. 
Some time after this horse was put into service by farmers, and during 
the latter part of the season, he developed symptoms of the disease, which 
was only in its incipiency when pronounced by the writer to be Maladie- 
Du-Coit, and stringent measures to prevent its spread were put in force 
at once. Later through co-operation of the Bureau of Animal Industry, 
this horse was shipped to Washington, D. C, with two mares, which were 
suffering from the same trouble. Our diagnosis was not only verified, but 
proved the occasion of one of the most interesting cases they had had. 
Subsequent action, almost brought about the quarantine of Iowa against 
the shipment of horses, but through the destruction of all other affected 
animals in Van Buren county, such measure was prevented. In all, 173 
mares and five stallions were placed in quarantine, and about twenty 
head of mares were killed, the state paying for three of them and the 
government paying owners for the others. This practically ended the 
existence of Maladie-Du-Coit in Iowa. Following is another photograph 
showing the horse while he was in an advanced stage of the disease, and 
by comparison with the first picture, it may be seen the disastrous effect 
produced by this disease. 
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