474 IOWA DEPARTMENT OF AGRICULTURE 
tion at hand I may express the following opinion: Sucn an acute devel- 
opment of tuberculosis as a result of tuberculin injection is to be feared 
only exceptionally, and then in cases of advanced tuberculosis. It must 
not be forgotten that acute miliary tuberculosis by no means rarely ac- 
companies an advanced tuberculosis of long standing. It is therefore 
impossible to offer strict proof of the casual connection with the injection, 
and only oft-repeated observation could ma^e this probably. In support 
of my vievv I offer the following: In the course of the last three years I 
have made careful postmortem examinations of 83 tuberculous animals, 
which have been removed from my experiment farm, Thurebylille. Among 
these were 18 (or, strictly speaking, 23) high-grade tuberculous animals. 
I have been able to prove miliary tuberculosis in only 4 of these. Among 
the others, w'hich showed less developed tuberculosis, I have never found 
miliary tuberculosis, and w'ith very many I have never found any sign 
of a more rapid development of the process. On the contrary, it has been 
proved that the disease was restricted locally, often for years, in spite 
of yearly repeated injections. Dissections w^ere made at very different 
periods after the injections — in 17 cases from four to twelve days after 
the last test. In all of these cases earlier tests had been made months 
or years before. In 28 cases the injection took place from nineteen days 
to two months before the butchering: In 3 of these cases earlier injec- 
tions had been made. In 38 cases from two anad one-half months to 
one year intervened betw^een the last injection and the dissection. Dis- 
section gives the best explanation of this question, but a clinical observa- 
tion continued for years, of a herd tested with tuberculin can render very 
essential aid. If Hess's opinion is correct, it is to be assumed that tu- 
berculosis must take an unusually vicious course in such herds, but this 
I have been unable to prove. At Thurbylille there has existed for three 
years a reacting division, consisting originally of 131 head and now of 
69. Although these animals are yearly tested, and although most of 
them react every year, the division certainly appears to be made up of 
healthy animals, and the farm inspector has expressed the decided 
opinion that the tuberculosis in this division is no more developed than 
at the beginning of the experiment. The testimony of many owners of 
large herds of cattle which have long ago been injecetd is to the same 
effect. I will adduce statements from several. A farm tenant whose 
cattle were injected tw^enty months previously, when 82 per cent of the 
grown animals reacted, wrote me recently as follows: "Only 2 cow& 
from the division of 100 head had been sold as decidedly tuberculous. 
The majority appeared afterwards, just as before, entirely healthy. The 
fat animals which had been slaughtered had been pronounced healthy by 
the butchers." Another farm tenant with a herd injected in 1894 had 
not been obliged to remove a single animal from the tuberculosis divi- 
sion, numbering 70 head. A large farm owner in Jutland stated in Sep- 
tember that he had traced no undesirable result from the injection. His 
herd of 350 had been injected in February and about 75 per cent reacted. 
Similar answers have been given by other owners and veterinarians. 
"A veterinarian who had injected 600 animals, among them a herd of a 
large farm, eighteen months previously, expressed the belief that the 
