OF A SILUROID; S. HIROTA. 373 



while the goblet cells are scattered or at least separated from one 

 another by interstitial cells. 



b) The goblet cells are usually multi-nucleated — containing 

 sometimes as m-my as four nuclei — while the glandular cells have 

 never more than one (Figs. 18 and 21). 



c) The goljlet cells which are deeply imbedded in the epidermis 

 have no opening, wliile the glandular cells are directly exposed 

 externally. 



d) The goblet cells are always much larger than the glandular 

 cells, being often as much as ten times in volume (Fig. 19). 



e) The glandular cells are Mdthout exception tilled with finely 

 granular thick contents, while the contents of the goblet cells are 

 partly or entirely very coarse-grained. 



f) As Fig. 19 shows, there is no gradual transition between 

 the goblet, and the glandular cells, an abrupt replacement takinf^ 

 place. 



In a young animal, such as is represented in Fig. 8, the glandular 

 cells of the dendritic appendage are as yet only slightly larger th;in 

 the surrounding epidermal cells, but they are already directly exposed 

 at one end in the bottom of diminutive pits (Fig. 22), although it is 

 doubtful whether they are actually functional or not. In such a stage 

 ditferences between these cells and the o-oblet cells are not as clear as 

 in the adult, but it is noteworthy that the former are found in groups, 

 while sucli is never the case with the o-oblet cells in anv stas'e. It 



o *■' <--- 



would, however, require further embryological research to decide 

 whether the glandular cells ;u-e metamorphosed goblet cells or are 

 independently developed in tliis particular organ. 



The first writer wlio pointed out the presence of the pits or 

 " Krypten " and of the glandular cells in the ap{)endage is Brock. 

 In his sections, he, however, found ordinary epidermal cells in the 



