536 IOWA DEPARTMENT OF AGRICULTURE 



I advised the feeding of same discontinued. The owner, being skeptical 

 in the matter, had a load of same hauled a distance of one and one- 

 half miles and fed to another herd with the results that two previously 

 healthy young cattle died in the same manner as above mentioned. The 

 discontinuance of feeding that hay had the desired effect. No more 

 became sick. Out of the forty or more affected, twenty-three died, which 

 made a total of fifty-six dead. The remaining seventeen or more recovered 

 gradually without medication of any kind. 



RABIES. 



Rabies is one of the oldest known diseases. It is described by 

 Aristotle in the fourth century B. C. Allusions to it are found in 

 Virgil, Ovid, Plutarch and Horace. Cornelius Celsus, first century 

 of Christian era, was the first to employ the term "hydrophobia." 

 No allusions are found to it in the literature of the Middle Ages. 

 Dioscorides recommended excision of wound as protective measure, 

 and Galen in the second century gives special remedies for rabies. 

 Baughin in 1591 gives account of the transmission of rabies from 

 wolves to man. In 1604 an epizootic of rabies broke out in Paris. 

 Toward the end of the seventeenth century it broke out in Italy, 

 and later in Germany and England. From 1779 to 1807 it ap- 

 peared in America. At about the same time the disease spread 

 over the whole of Europe. Chabert and Hunter conducted nota- 

 ble investigations into the nature of the disease at this time. 

 Viborg, in Copenhagen, and "Waldinger, in Vienna, improved 

 methods of investigations of rabies about 1815. Delebere, Blaine 

 and Greve in England in 1818 greatly enriched clinical knowledge 

 of the disease. Hertwig in 1828 published a report of many ex- 

 periments which were of great value. Virchow, in 1854, exposed 

 the error of the belief that heat, passion, etc., could cause rabies. 

 It is only in recent years that the exclusively infective nature 

 of the disease has become recognized. In 1881 Pasteur gave his 

 discovery of inoculative treatment to the world. 



The infective matter of rabies has not yet been produced in a 

 pur" condition, though Pasteur has shown that the virus is purest 

 in the central nervous system of infected animals, and less so in 

 the peripheral nerves, salivary glands, lachrymal glands, aqueous 

 humor of the eye, pancreas, mamma, testicles, kidneys and their 

 secretions. 



