UPON HEALTH AND METABOLISM. 



309 



and in addition to that a number of calculators were employed to 

 tabulate, classify, and average the data. The experimental data 

 which were obtained are published in Bureau of Chemistry Bulletin 

 84, which when completed will contain the entire series of studies. 

 Part I, of Bulletin 84, is devoted to the detailed study of the effect 

 of borates and boric acid upon health and metabolism. This part 

 of the Bulletin consists of 477 pages. Part II is devoted to the 

 study of salicylic acid and salicylates and contains 283 pages. Part 

 III contains the data relating to sulphurous acid and sulphites, and 

 contain 281 pages, making a total of published matter of 1,041 

 pages. 



Changes in the Urinary Nitrogen and Sulphur Compounds.^ 



The data relating to benzoic acid and benzoates are in press. 

 These data, together with those relating to the other parts of the 

 study which have been completed and submitted for publication, 

 will make a volume of approximately 2,100 pages. All that I can 

 give in this paper will be the general conclusions relating to each 

 part of the study. 



Conclusions. 



Boric Acid and Borates. — In the consideration of the action of 



preservatives of a mineral nature, such as borax and boric acid, 



it must be remembered that the animal as well as the plant possesses 



^ ]\Iinus and plus signs indicate decreased or increased total excretion in 

 preservative period as compared with the fore period. 



