306 CARNEGIE INSTITUTION OF WASHINGTON. 



(8) Factors affecting basal metabolism. Francis G. Benedict. Joui-n. Biol. Chem., 20, 



263 (1915). 



As a result of several years' experimentation with normal men and women 

 of different ages, heights, and weights, and the additional data furnished by 

 observations on animals, infants, and particularly a studj^ of a fasting man, 

 general conclusions with regard to the factors affecting basal metabolism are 

 formed. The data all point toward the fact that the mass of protoplasmic 

 tissue is capable of being stimulated to varying degrees of intensity and that 

 this mass of tissue, together with the stimulus, determines the metabolism. 

 That under a large number of conditions the metabolism is roughly propor- 

 tional to the body-surface is admitted, but that there is any causal relationship 

 between body-surface and metabolism is denied. For practical purposes, the 

 surface area, either as roughly computed by a standard formula or more par- 

 ticularly by the refined method of DuBois, gives an approximate picture of the 

 basal metabolism. The factors affecting basal metabolism are continually 

 in play, and the result is that nothing approximating constancy in relation 

 between surface area and metabolism can be expected in individual cases. 



(9) The factors affecting normal basal metabolism. Francis G. Benedict. Proc. Nat. Acad. 



Sci., 1, 105 (1915). 



An abbreviated presentation of the material in the foregoing article. 



(10) A respiration apparatus for small animals. Francis G. Benedict. Journ. Biol. Chem., 



20, 301 (1915). 



An adaptation has been made of the universal respiration apparatus to the 

 study of both the oxygen consumption and the carbon-dioxide production of 

 small animals. The apparatus has been tested by control tests, and readily 

 permits a study of the influence of special environmental atmospheres upon 

 the metabolism. The apparatus is at present in use in a study of the influ- 

 ence of high-oxygen atmospheres upon the metabolism of small animals. 



(11) Investigations at the Nutrition Laboratory of the Carnegie Institution of Washington, 



Boston, Massachusetts. Francis G. Benedict. Science, 42, 75 (1915). 



A popular presentation of the general methods and results of investigations 

 carried out in the Nutrition Laboratory. The paper is accompanied by a 

 metabolism chart of a man fasting 31 days. 



(12) A calorimetric calibration of the Krogh bicycle ergometer. Francis G. Benedict and 



Louis E. Emmes. Am. Journ. Physiol., 38, 52 (1915). 



Of the forms of apparatus used for measuring the severe muscular work of 

 man, that of the bicycle has proved most satisfactory. The ingenious form of 

 bicycle ergometer devised by Dr. August Krogh, of Copenhagen, has been 

 purchased by the Nutrition Laboratory and a series of calibrations made inside 

 the chair calorimeter. These calibrations followed the technique of those 

 made of an earlier and less perfect form of ergometer, the results of which were 

 given in Publication No. 167 of the Carnegie Institution of Washington. The 

 Krogh electric-brake bicycle ergometer was placed inside of the chair calorim- 

 eter and rotated from the outside by means of an electric motor. The exper- 

 iments showed that friction and other factors may be entirely neglected in 

 using the Krogh ergometer. Tests were made at different rates of speed and 

 ^vith different weights on the balance pan. 



(13) The energy metabolism of an infant with congenital absence of the cerebral hemi- 



spheres. Fritz B. Talbot. Arch. Pediatrics, 32, 452 (1915). 



The important relation between the brain and metabolism gave added 

 interest to a study of a human infant with absence of the cerebral hemi- 

 spheres. Since this infant was deprived of the volitional areas of the brain, its 



