276 CARNEGIE INSTITUTION OF WASHINGTON. 



two respiration chambers with a single universal respiration apparatus. 

 It was thus possible to conduct simultaneous experiments with a tor- 

 toise in one chamber and a Cuban boa in the other, and to secure 

 accurate observations in 24-hour periods. 



CLINICAL RESPIRATION CHAMBER. 



As a result of the development of a clinical respiration chamber, 

 which has been in progress for several years past, a complete apparatus 

 was installed in the New England Deaconess Hospital. During the 

 summer a research laboratory was constructed by the authorities of the 

 hospital in the basement of the building for the use of the Nutrition 

 Laboratory in respiration researches. The cUnical respiration chamber 

 is, at the moment of writing, being transferred to this new research 

 laboratory. 



INFANT RESPIRATION CHAMBER. 



The conclusion of our accumulation of data with infants from birth 

 to 1^ years of age has led to the study of infants of approximately 2 

 years of age, thus requiring the use of a larger respiration chamber to 

 accommodate the larger body of the infant. Such a chamber has been 

 constructed and is being regularly employed for studying the older 

 infants in the Massachusetts Wet Nurse Directory. 



RESPIRATION CALORIMETER FOR SMALL ANIMALS. 



For some time the Laboratory has been endeavoring to develop a 

 respiration calorimeter for small animals which would overcome the 

 objection to many existing types, especially as to the large mass of 

 metal frequently employed. After several years of unsuccessful experi- 

 mentation a type was devised during the past year which has proved 

 especially sensitive. This apparatus has already been used for a 

 study including the measurement of the gaseous metabolism and of the 

 direct and indirect calorimetry of fasting geese. 



Thanks to the personal interest of Professor Eliliu Thomson, of the 

 General Electric Company, of Lynn, two meters were designed and con- 

 structed for use in connection with this calorimeter. These meters 

 possess certain special features for measuring the amount of electrical 

 energy actually delivered. The successful construction of the meters 

 made possible the completion of the new respiration calorimeter. 



LARGE RESPIRATION CHAMBER. 



In the original design of the Nutrition Laboratory space was provided 

 in the calorimeter laboratory for the construction of a large respiration 

 chamber which would permit the study of the gaseous metabolism of a 

 number of individuals simultaneously or of a few individuals working to 

 the limit of human endurance. The construction of this apparatus was 

 deferred until the decision was made as to whether or not calorimetric 



